145626-93-3 Usage
Description
BIS(2-MERCAPTOETHYL) SULFONE DISULFIDE, also known as Bis(2-mercaptoethyl) sulfone, is a white crystalline solid with unique chemical properties. It is a disulfide compound that has the ability to reduce disulfide bonds in aqueous solutions, making it a valuable reagent in various applications.
Uses
Used in Biochemical Research:
BIS(2-MERCAPTOETHYL) SULFONE DISULFIDE is used as a reagent for the reduction of disulfide bonds in aqueous solutions, facilitating the study of protein structure and function. Its effectiveness as a substitute for DTT (Dithiothreitol) makes it a preferred choice in many research settings.
Used in Pharmaceutical Industry:
BIS(2-MERCAPTOETHYL) SULFONE DISULFIDE is used as an intermediate in the synthesis of various pharmaceutical compounds, particularly those involving disulfide bond formation or reduction. Its ability to reduce disulfide bonds makes it a valuable tool in drug development and synthesis processes.
Used in Cosmetics Industry:
In the cosmetics industry, BIS(2-MERCAPTOETHYL) SULFONE DISULFIDE is used as an ingredient in the formulation of hair and skin care products. Its reducing properties help to improve the texture and appearance of hair, as well as provide skin with a smoother and more youthful appearance.
Used in Environmental Applications:
BIS(2-MERCAPTOETHYL) SULFONE DISULFIDE is used as a reagent in environmental analysis and monitoring, particularly for the detection and quantification of disulfide compounds in water samples. Its ability to reduce disulfide bonds makes it a valuable tool in assessing water quality and identifying potential contaminants.
Check Digit Verification of cas no
The CAS Registry Mumber 145626-93-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,6,2 and 6 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 145626-93:
(8*1)+(7*4)+(6*5)+(5*6)+(4*2)+(3*6)+(2*9)+(1*3)=143
143 % 10 = 3
So 145626-93-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H8O2S3/c5-9(6)3-1-7-8-2-4-9/h1-4H2
145626-93-3Relevant articles and documents
Synthesis of Dithiols as Reducing Agents for Disulfides in Neutral Aqueous Solution and Comparison of Reduction Potentials
Lamoureux, Guy V.,Whitesides, George M.
, p. 633 - 641 (2007/10/02)
Several dithiols have been prepared that are useful for the reduction of disulfides in aqueous solution.The reduction potential of these thiols have been determined from the measurement of the equilibrium constant of thiol/disulfide interchange with oxidized dithiothreitol using a 1H NMR assay.The values of pKa of some of the dithiols were measured to estimate their rate of reduction of disulfides.Bis(2-mercaptoethyl) sulfone (2), N,N'-dimethyl-N,N'-bis(mercaptoacetyl)hydrazine (5), and meso-2,5-dimercapto-N,N,N',N'-tetramethyladipamide (6) are especially interesting as alternatives to dithiothreitol for the reduction of disulfides.
