1456712-38-1

Basic information

• Product Name: (2S,3R,4R,5R)-5-(2,4-diaminoimidazo[2,1-f][1,2,4]-triazin-7-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
• CAS NO: 1456712-38-1
• Molecular Weight: 284.25
• Mol File: 1456712-38-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3R,4R,5R)-5-(2,4-diaminoimidazo[2,1-f][1,2,4]-triazin-7-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R,4R,5R)-5-(2,4-diaminoimidazo[2,1-f][1,2,4]-triazin-7-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol(1456712-38-1)
• EPA Substance Registry System: (2S,3R,4R,5R)-5-(2,4-diaminoimidazo[2,1-f][1,2,4]-triazin-7-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol(1456712-38-1)

Safety Data

• Hazardous Substances Data: 1456712-38-1(Hazardous Substances Data)

Usage

Description

(2S,3R,4R,5R)-5-(2,4-diaminoimidazo[2,1-f][1,2,4]-triazin-7-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol is a complex nucleoside analog with a tetrahydrofuran backbone, a fluorine atom at position 4, and a 2,4-diaminomidazo[2,1-f][1,2,4]-triazin-7-yl group. This unique chemical structure is characterized by the presence of two amino groups and a triazinyl ring, which may contribute to its significant biological activity.

Uses

Used in Pharmaceutical Industry:
(2S,3R,4R,5R)-5-(2,4-diaminoimidazo[2,1-f][1,2,4]-triazin-7-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol is used as a potential antiviral agent for the treatment of infections caused by DNA viruses. Its unique structure, including the fluoro and hydroxymethyl groups, suggests that it may inhibit viral DNA replication or protein synthesis, thus exhibiting significant biological activity in combating viral infections.
Further research would be necessary to determine the specific pharmacological properties and potential therapeutic applications of this compound, as well as its safety and efficacy in clinical settings.

Upstream product

• 1355049-97-6 (3R,4R,5R)-4-(benzyloxy)-5-((benzyloxy)methyl)-3-fluorodihydrofuran-2(3H)-one 
• 1456712-33-6 (2S,3R,4R,5R)-4-(benzyloxy)-5-(benzyloxymethyl)-2-(2,4-bis(methylthio)imidazo[2,1-f][1,2,4]triazin-7-yl)-3-fluorotetrahydrofuran-2-ol 
• 1456712-34-7 (2S,3R,4R,5R)-7-(4-(benzyloxy)-5-(benzyloxymethyl)-3-fluorotetrahydrofuran-2-yl)-2,4-bis(methylthio)imidazo[2,1-f][1,2,4]-triazine 
• 1456712-35-8 (2S,3R,4R,5R)-7-(4-(benzyloxy)-5-(benzyloxymethyl)-3-fluorotetrahydrofuran-2-yl)-2-(methylthio)imidazo[2,1-f][1,2,4]-triazin-4-amine 
• 1456712-36-9 (2S,3R,4R,5R)-7-(-4-(benzyloxy)-5-(benzyloxymethyl)-3-fluorotetrahydrofuran-2-yl)-2-(methylsulfonyl)imidazo[2,1-f][1,2,4]triazin-4-amine 
• 1456712-37-0 (2S,3R,4R,5R)-7-(4-(benzyloxy)-5-(benzyloxymethyl)-3-fluorotetrahydrofuran-2-yl)imidazo[2,1-f][1,2,4]-triazine-2,4-diamine 
• 1062135-87-8 7-bromo-2,4-bis(methylthio)imidazo[2,1-f][1,2,4]triazine 

Relevant articles and documents

2'-SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT

Provided are compounds of Formula I, as well as pharmaceutical compositions containing compounds of Formula I and methods for treating Orthomyxoviridae virus infections by administering these compounds. The compounds, compositions, and methods provided are particularly useful for the treatment of Human Influenza virus infections.