1456809-26-9Relevant articles and documents
Bifunctional coumarin derivatives that inhibit transthyretin amyloidogenesis and serve as fluorescent transthyretin folding sensors
Myung, Nojoon,Connelly, Stephen,Kim, Boyoung,Park, Sung Jean,Wilson, Ian A.,Kelly, Jeffery W.,Choi, Sungwook
supporting information, p. 9188 - 9190 (2013/09/24)
We describe coumarin derivatives that are non-fluorescent in aqueous buffers and that very selectively bind to transthyretin (TTR) in complex biological environments potently inhibiting TTR amyloidogenesis while also exhibiting sensitive off-on fluorescen