145731-78-8

Basic information

• Product Name: nicotinic acid N₂-(3-phenylallylidene)hydrazide
• Synonyms: nicotinic acid N₂-(3-phenylallylidene)hydrazide
• CAS NO: 145731-78-8
• Molecular Weight: 251.288
• Mol File: 145731-78-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: nicotinic acid N₂-(3-phenylallylidene)hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: nicotinic acid N₂-(3-phenylallylidene)hydrazide(145731-78-8)
• EPA Substance Registry System: nicotinic acid N₂-(3-phenylallylidene)hydrazide(145731-78-8)

Safety Data

• Hazardous Substances Data: 145731-78-8(Hazardous Substances Data)

Upstream product

• 614-18-6 3-pyridinecarboxylic acid ethyl ester 
• 553-53-7 Nicotinic acid hydrazide 
• 104-55-2 3-phenyl-propenal 
• 59-67-6 nicotinic acid 
• 14371-10-9 (E)-3-phenylpropenal 

Relevant articles and documents

Synthesis method of nicotinoyl hydrazone Schiff base compound as well as application of compound to bactericide

The invention relates to a synthesis method of a nicotinoyl hydrazone Schiff base compound as well as application of the compound to bactericide, and relates to the technical field of organic synthesis. The synthesis method of the nicotinoyl hydrazone Schiff base compound comprises two steps of synthesizing an intermediate nicotinoylhydrazine and synthesizing a target product, wherein the nicotinoylhydrazine is prepared by carrying out a refluxing stirring reaction among raw materials such as hydrazine hydrate, ethyl nicotinate and absolute ethanol, carrying out a reaction under the conditionof 80 DEG C for synthesis, and performing aftertreatment; the target product is prepared by performing refluxing stirring reaction on the prepared intermediate nicotinoylhydrazine as well as a small amount of glacial acetic acid and aldehyde compound under the condition of 65 DEG C, performing suction filtration and performing recrystallization. The synthesis reaction is simple to operate and theyield of products is high; furthermore, the synthesis method is low in equipment requirement, low in production cost and easy in industrialized large-scale application. In addition, the synthesized nicotinoyl hydrazone Schiff base compound can serve as the bactericide to selectively kill germs, and the prevention effect on wheat powdery mildew can reach to 83.1 percent.