145758-05-0 Usage
Description
3,4-Difluorobenzenesulfonyl chloride is an organic compound characterized by the presence of two fluorine atoms at the 3rd and 4th positions of a benzene ring, with a sulfonyl chloride group attached to the benzene ring. It is a clear light yellow to yellow liquid and is known for its chemical reactivity and stability.
Uses
Used in Pharmaceutical Industry:
3,4-Difluorobenzenesulfonyl chloride is used as a synthetic intermediate for the production of various pharmaceutical compounds. Its unique chemical structure allows it to be a key component in the synthesis of specific drugs, such as 1-benzyl-3-bromo-2-(3,4-difluorophenyl)indole and 1-benzyl-2-(3,4-difluorophenyl)indole. These synthesized compounds have potential applications in the treatment of various medical conditions.
Used in Chemical Research:
In the field of chemical research, 3,4-difluorobenzenesulfonyl chloride serves as a valuable reagent for conducting various chemical reactions and experiments. Its distinct properties make it suitable for exploring new chemical pathways and developing novel compounds with potential applications in various industries.
Used in Material Science:
3,4-Difluorobenzenesulfonyl chloride can also be utilized in the development of new materials with specific properties. Its incorporation into polymers or other materials can lead to enhanced characteristics, such as improved stability, reactivity, or selectivity, which can be beneficial in various applications, including electronics, coatings, and adhesives.
Check Digit Verification of cas no
The CAS Registry Mumber 145758-05-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,7,5 and 8 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 145758-05:
(8*1)+(7*4)+(6*5)+(5*7)+(4*5)+(3*8)+(2*0)+(1*5)=150
150 % 10 = 0
So 145758-05-0 is a valid CAS Registry Number.
InChI:InChI=1/C18H19F21O3Si/c1-4-40-43(41-5-2,42-6-3)8-7-9(19,20)10(21,22)11(23,24)12(25,26)13(27,28)14(29,30)15(31,32)16(33,34)17(35,36)18(37,38)39/h4-8H2,1-3H3
145758-05-0Relevant articles and documents
Synthesis and characterization of polyethersulfone with intrinsic microporosity
Lee, Kyuchul,Jeon, Jun Woo,Maeng, Bo Mi,Huh, Kang Moo,Chan Won, Jong,Yoo, Youngjae,Kim, Yong Seok,Kim, Byoung Gak
, p. 70320 - 70325 (2016)
Polymers with intrinsic microporosity (PIMs) are usually ladder-type polymers that adopt a spiro structure. In the present study, a new non-ladder-type polyethersulfone-type PIM that incorporates a linear sulfone moiety was synthesized. Brunauer-Emmett-Te
Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists
-
, (2008/06/13)
The present invention relates to urotensin II receptor antagonists, CCR-9 antagonists, pharmaceutical compositions containing them and their use.
Topically active carbonic anhydrase inhibitors. 4. [(hydroxyalkyl)sulfonyl]benzene and [(hydroxyalkyl)sulfonyl]thiophenesulfonamides
Shepard,Graham,Hudcosky,Michelson,Scholz,Schwam,Smith,Sondey,Strohmaier,Smith,Sugrue
, p. 3098 - 3105 (2007/10/02)
For several decades a tantalizing goal for the treatment of primary open-angle glaucoma has been the development of a topically active carbonic anhydrase inhibitor. Recent results from several research groups indicate that considerable progress has been made toward this objective. In this report, we present the design and synthesis of (hydroxyalkyl)sulfonyl-substituted benzene- and thiophenesulfonamides. These compounds exhibit inhibition of carbonic anhydrase II in the nanomolar range and lower intraocular pressure in the α-chymotrypsinized rabbit model of ocular hypertension after topical instillation.
