145781-78-8

Basic information

• Product Name: S-(2-acetamidoethyl) (E)-3-phenylprop-2-enethioate
• Synonyms: S-(2-acetamidoethyl) (E)-3-phenylprop-2-enethioate
• CAS NO: 145781-78-8
• Molecular Weight: 249.334
• Mol File: 145781-78-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: S-(2-acetamidoethyl) (E)-3-phenylprop-2-enethioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-(2-acetamidoethyl) (E)-3-phenylprop-2-enethioate(145781-78-8)
• EPA Substance Registry System: S-(2-acetamidoethyl) (E)-3-phenylprop-2-enethioate(145781-78-8)

Safety Data

• Hazardous Substances Data: 145781-78-8(Hazardous Substances Data)

Upstream product

• 1190-73-4 2-(acetylamino)ethanethiol 
• 140-10-3 (E)-3-phenylacrylic acid 

Downstream Products

• 2082-94-2 4-hydroxy-6-<(E)-2-phenylethenyl>-2H-pyran-2-one 
• 539827-21-9 (E)-4-hydroxy-6-(2-oxo-4-phenylbut-3-enyl)-2H-pyran-2-one 
• 480-39-7 pinocembrin 

Relevant articles and documents

In vitro precursor-directed synthesis of polyketide analogues with coenzyme a regeneration for the development of antiangiogenic agents

Polyketide analogues are produced via in vitro reconstruction of a precursor-directed polyketide biosynthetic pathway. Malonyl-CoA synthetase (MCS) was used in conjunction with chalcone synthase (CHS), thereby allowing efficient use of synthetic starter molecules and malonate as extender. Coenzyme-A was recycled up to 50 times. The use of a simple immobilization procedure resulted in up to a 30-fold higher yield of pyrone CHS products than that obtained with the free enzyme solutions.