1458656-71-7

Basic information

• Product Name: 2-((S)-6-((R)-7-fluoro-4-(4-(3-hydroxy-3-methylbutoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
• Synonyms: 2-((S)-6-((R)-7-fluoro-4-(4-(3-hydroxy-3-methylbutoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetic acid
• CAS NO: 1458656-71-7
• Molecular Weight: 534.625
• Mol File: 1458656-71-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-((S)-6-((R)-7-fluoro-4-(4-(3-hydroxy-3-methylbutoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((S)-6-((R)-7-fluoro-4-(4-(3-hydroxy-3-methylbutoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetic acid(1458656-71-7)
• EPA Substance Registry System: 2-((S)-6-((R)-7-fluoro-4-(4-(3-hydroxy-3-methylbutoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetic acid(1458656-71-7)

Safety Data

• Hazardous Substances Data: 1458656-71-7(Hazardous Substances Data)

Upstream product

• 1985-88-2 4-chloro-2-methyl-2-butanol 
• 1458652-57-7 (S)-4-bromo-7-fluoro -2,3-dihydro-1H-inden-1-ol 
• 1003048-72-3 4-bromo-7-fluoro-2,3-dihydro-1H-inden-1-one 
• 1294453-62-5 4-(4-bromo-3,5-dimethyl-phenoxy)-2-methyl-butan-2-ol 
• 2568-33-4 3-methyl-butane-1,3-diol 
• 17689-66-6 3-hydroxy-3-methylbutyl toluene-4-sulfonate 
• 1458652-64-6 methyl 2-((S)-6-((R)-7-fluoro-4-(4-(3-hydroxy-3-methylbutoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetate 
• 108-46-3 recorcinol 
• 25392-41-0 4-chloromethyl-7-hydroxycoumarin 

Relevant articles and documents

PROCESS AND INTERMEDIATES FOR PREPARING INDANYLOXYDIHYDROBENZOFURANYL ACETIC ACID DERIVATIVES AS GPR40 AGONISTS

The present invention relates to compounds of formula (I) werein Rs denotes F or CF3, Ra denotes H or C1-4-alkyl and Z denotes a leaving group or an optionally substituted or protected hydroxyl group, suitable a

NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACID DERIVATIVES AND THEIR USE AS GPR40 RECEPTOR AGONISTS

The present invention relates to compounds of general formula (I), wherein the groups R1, R2 and m are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.

NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACID DERIVATIVES AND THEIR USE AS GPR40 RECEPTOR AGONISTS

The present invention relates to compounds of general formula I, (I), wherein the groups R1, R2 and m are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.