145903-73-7

Basic information

• Product Name: piperidine salt of (E,Z)-5-(2-hydroxyphenylmethylene)-4-oxo-2-thioxothiazolidine
• CAS NO: 145903-73-7
• Molecular Weight: 322.452
• Mol File: 145903-73-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: piperidine salt of (E,Z)-5-(2-hydroxyphenylmethylene)-4-oxo-2-thioxothiazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: piperidine salt of (E,Z)-5-(2-hydroxyphenylmethylene)-4-oxo-2-thioxothiazolidine(145903-73-7)
• EPA Substance Registry System: piperidine salt of (E,Z)-5-(2-hydroxyphenylmethylene)-4-oxo-2-thioxothiazolidine(145903-73-7)

Safety Data

• Hazardous Substances Data: 145903-73-7(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 81154-12-3 (5Z)-5-(2-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one 

Downstream Products

• 345932-21-0 5-(2-hydroxyphenylmethylene)-2-(4-methylphenylimino)-4-oxothiazolidine 
• 81182-99-2 5-(2-hydroxyphenylmethylene)-2-piperidino-4-oxo-2-thiazoline 
• 101444-73-9 5-(2-hydroxyphenylmethylene)-2-benzylimino-4-oxothiazolidine 
• 81154-06-5 E-5-(2-hydroxyphenylmethylene)-2-morpholino-4-oxo-2-thiazoline 

Relevant articles and documents

Reactions of 5-Arylmethylene-4-oxo-2-thioxothiazolidines with Amines

Piperidine, morpholine and benzylamine react with 5-arylmethylene-4-oxo-2-thioxothiazolidines (I) to give the corresponding piperidine (IIa-d), morpholine (IIe-f) and benzylamine (IIg) salts which on treatment with ethanol undergo decomposition to give the respective 2-piperidino- and 2-morpholino-4-oxo-2-thiazolines (III), and 2-benzylimino-4-oxothiazolidine (IVa).However, decomposition of IIa-d in the presence of an equimolar amount of morpholine gives mixtures of 2-piperidino- and 2-morpholino-4-oxo-2-thiazolines (III).Furthermore, decomposition of IIe, c and d inthe presence of an excess of a primary amine affords exclusively the respective 2-substituted-imino-4-oxo-thiazolidines (IV).Cleavage of 5-arylmethylene-3-methyl-4-oxo-2-thioxothiazolidines (Va-b and e-g) with excess of piperidine affords 1-(N-methylthiocarbamyl)piperidine (VI).The structures of II, III, IV and VI are based on analytical and spectral data.