145934-89-0Relevant articles and documents
Extending the scope of the aza-Fischer synthesis of 4- and 6-azaindoles
Thomae, David,Jeanty, Matthieu,Coste, Jerome,Guillaumet, Gerald,Suzenet, Franck
, p. 3328 - 3336 (2013/07/05)
Fischer indole cyclization has recently been described as an efficient approach to the synthesis of azaindoles bearing electron-donating groups. We now show that this cascade reaction can be very efficient for the formation of a wider range of 4- and 6-azaindoles by using microwave irradiation. Fischer indole cyclization starting from aminopyridines is a very efficient cascade sequence leading to 4- and 6-azaindoles. The scope of the substituents on the pyridine ring was extended to include halogens and to weakly electron-donating substituents by using microwave irradiation. Copyright
INDOLIN PHENYLSULFONAMIDE DERIVATIVES
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Page/Page column 51; 52, (2010/11/30)
The invention relates to novel substituted indolin phenylsulfonamide derivatives, to a method for the production thereof and to the use thereof in medicaments, especially as potent PPAR-delta activating compounds for the prophylaxis and/or treatment of cardiovascular diseases, especially dyslipidaemia and coronary heart diseases.
ACTIVE COMPOUNDS
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, (2008/06/13)
Therapeutically active compounds of the formula: wherein the variables are defined in the specification are provided