1460-06-6Relevant articles and documents
Transition metal free large-scale synthesis of aromatic vinyl chlorides from aromatic vinyl carboxylic acids using bleach
Hatvate, Navnath T.,Takale, Balaram S.,Ghodse, Shrikant M.,Telvekar, Vikas N.
supporting information, p. 3892 - 3894 (2018/10/02)
While continuing our research on Hunsdiecker reaction, we came across an interesting application of bleach, sodium hypochlorite (NaOCl) for decarboxylative chlorination reaction. The reaction is easily scaled up to 10 mmol. The reaction has good tolerance towards wide variety of functional groups. The reaction has mild conditions and gave relatively high chemical yield of the desired product.
Diphenylmethylchlorocarbene: Comparison of experiment and theory
Moss, Robert A.,Wei, Ma
, p. 5101 - 5104 (2007/10/03)
Diphenylmethylchlorocarbene (5) exhibits minimal 1,2-Ph migration (k(Ph)=1.5x106 s-1); 1,2-H migration (k(H)=2.1x107 s-1) is 14 times faster in pentane at 25°C.
A one-pot generation of α-chloro-α-lithio alkanephosphonates. A new preparative route to 1,2-epoxyalkanephosphonates
Lee,Shin,Oh
, p. 649 - 655 (2007/10/02)
Reaction of lithio anion derived from diethyl alkanephosphonate in the presence of 2 eq. of n-BuLi with benzenesulfonyl chloride gives directly the corresponding diethyl-1-chloro-1-lithioalkanephosphonate, which reacts in situ with carbonyl compounds followed by intramolecular substitution reaction to give 1,2-epoxyalkanephosphonates.