14618-12-3

Basic information

• Product Name: Propanedioic acid, (1-phenylethyl)-, diethyl ester
• CAS NO: 14618-12-3
• Molecular Formula: C15H20O4
• Molecular Weight: 264.321
• Mol File: 14618-12-3.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, (1-phenylethyl)-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, (1-phenylethyl)-, diethyl ester(14618-12-3)
• EPA Substance Registry System: Propanedioic acid, (1-phenylethyl)-, diethyl ester(14618-12-3)

Safety Data

• Hazardous Substances Data: 14618-12-3(Hazardous Substances Data)

Upstream product

• 1462-12-0 diethyl ethylidenemalonate 
• 996-82-7 sodium diethylmalonate 
• 672-65-1 (1-chloroethyl)benzene 
• 996-82-7 sodium diethylmalonate 
• 585-71-7 (1-bromoethyl)benzne 
• 917-64-6 methyl magnesium iodide 
• 5292-53-5 diethyl benzalmalonate 
• 105-53-3 diethyl malonate 
• 71478-47-2 phenylmanganese(II) chloride 
• 74-88-4 methyl iodide 
• 5294-56-4 2-(1-phenylethylidene)malonic acid diethyl ester 
• 1184-58-3 dimethylaluminum chloride 
• 98-85-1 1-Phenylethanol 
• 100-52-7 benzaldehyde 

Downstream Products

• 14237-62-8 isopropyl-(1-phenyl-ethyl)-malonic acid diethyl ester 
• 35205-58-4 ethyl 2-methyl-2-carboethoxy-3-phenylbutyrate 
• 137155-58-9 ethyl β-phenylaminobutyrate 
• 150903-48-3 (S)-2-[2-Acetylsulfanylmethyl-3-(4-hydroxy-phenyl)-butyrylamino]-3-(4-hydroxy-phenyl)-propionic acid benzyl ester 
• 1026466-91-0 2-Methylene-3-(4-nitro-phenyl)-butyric acid ethyl ester 
• 155943-78-5 2-Methylene-3-(4-nitro-phenyl)-butyric acid 
• 37556-09-5 (1-p-Nitro-phenylethyl)-malonsaeurediethylester 
• 1134-71-0 ethyl 3-phenylbutanoate 
• 4593-90-2 3-phenylbutyric acid 
• 41103-90-6 (1-phenyl-ethyl)-malonic acid 
• 111654-25-2 3-phenoxybenzyl 3-methyl-3-phenylpropionate 
• 1333257-51-4 (+/-)-5,7-dihydroxy-6-(1-phenylethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile 
• 1333257-54-7 (+/-)-5,7-dichloro-6-(1-phenylethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile 
• 1333257-43-4 (+/-)-5-chloro-7-hydroxy-6-(1-phenylethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile 

Relevant articles and documents

Preparation method and application of chiral spiro aminophosphine ligand with substituent at 3-position of pyridine ring

The invention relates to a preparation method and application of a chiral spiro aminophosphine ligand with a substituent at the 3-position of a pyridine ring. The chiral spiro aminophosphine ligand isa compound shown as a formula 1, or a racemate or an op

Unnatural α-amino ethyl esters from diethyl malonate or ethyl β-bromo-α-hydroxyiminocarboxylate

We have explored here the scope of the age-old diethyl malonate-based accesses to α-amino esters involving Knoevenagel condensations of diethyl malonate on aldehydes, reductions of the resulting alkylidenemalonates, the preparation of the corresponding α-hydroxyimino esters and their final reduction. This synthetic pathway turned out to be general although some unexpected limitations were encountered. The synthetic modifications of some of the intermediates - using Suzuki-Miyaura coupling or cycloadditions - before undertaking the oximation step - provided accesses to further α-amino esters. Moreover, other pathways to α-hydroxyimino esters were explored including an attempt to improve the cycloadditions between ethyl β-bromo-α-hydroxyiminocarboxylate and various alkylfuranes.

Fe(HSO4)3 : An efficient, heterogeneous and reusable catalyst for C-alkylation of β-dicarbonyl compounds

Fe(HSO4)3(FHS) was used as an efficient catalyst for the heterogeneous addition of a series of benzylic and allylic alcohols to various β-dicarbonyl compounds, which afforded moderate to excellent yields of C-alkylated products in 1,2-dichloroethane. In comparison with the previous methods, the present research surprisingly exhibited higher reaction yields without formation of any by-products which could be formed by self-condensation of alcohols. Moreover, the catalyst can be readily recovered and reused up to five times with almost maintained reactivity and yields.