146369-65-5 Usage
Description
H-TYR-TIC-PHE-PHE-OH is a peptide chemical compound with the amino acid sequence H-Tyrosine-Threonine-Isoleucine-Phenylalanine-Phenylalanine-OH. It is a synthetic peptide with potential applications in research and pharmaceutical development.
Used in Research and Pharmaceutical Development:
H-TYR-TIC-PHE-PHE-OH is used as a research tool for studying peptide receptor interactions, protein-protein interactions, and structure-function relationships. Its specific sequence of amino acids may confer certain biological or pharmacological properties, making it a valuable compound for understanding peptide-mediated signaling pathways.
Used in Drug Development for Neurological or Psychiatric Disorders:
H-TYR-TIC-PHE-PHE-OH has potential therapeutic applications in the development of new drugs for the treatment of neurological or psychiatric disorders. Its unique amino acid sequence may contribute to its efficacy in targeting specific receptors or pathways involved in these conditions.
Further research is needed to fully understand the properties and potential applications of H-TYR-TIC-PHE-PHE-OH, as its specific biological or pharmacological properties have not yet been fully elucidated.
Check Digit Verification of cas no
The CAS Registry Mumber 146369-65-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,3,6 and 9 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 146369-65:
(8*1)+(7*4)+(6*6)+(5*3)+(4*6)+(3*9)+(2*6)+(1*5)=155
155 % 10 = 5
So 146369-65-5 is a valid CAS Registry Number.
InChI:InChI=1/C37H38N4O6/c38-29(20-22-13-15-27(42)16-14-22)35(44)31(25-9-2-1-3-10-25)33(37(46)47)41-36(45)30(39)21-23-7-6-11-26(19-23)34(43)32-28-12-5-4-8-24(28)17-18-40-32/h1-5,7-10,12-18,26,29-31,33,42H,6,11,19-21,38-39H2,(H,41,45)(H,46,47)/t26-,29-,30-,31?,33-/m0/s1
146369-65-5Relevant articles and documents
Side chain methyl substitution in the δ-opioid receptor antagonist TIPP has an important effect on the activity profile
Tourwé, Dirk,Mannekens, Els,Diem, Trang Nguyen Thi,Verheyden, Patricia,Jaspers, Hendrika,T?th, Géza,Péter, Antal,Kertész, Istvan,T?r?k, Gabriella,Chung, Nga N.,Schiller, Peter W.
, p. 5167 - 5176 (2007/10/03)
The δ-opioid antagonist H-Tyr-Tic-Phe-Phe-OH (TIPP-OH) or its C- terminal amide analogue was systematically modified topologically by substitution of each amino acid residue by all stereoisomers of the corresponding β-methyl amino acid. The potency and se
DELTA OPIOID RECEPTOR ANTAGONISTS AND THEIR USE AS ANALGESIC AGENTS
-
, (2008/06/13)
Compounds of the formula I as well as a process for their preparation, their pharmaceutical preparations and their use H--Tyr--Tic--X (I) wherein X is--Phe--OH,--Phe--NH 2,--Phe--Phe--OH, --Phe--Phe--NH 2,--Trp--Phe--NH 2, --Trp--Phe--OH,--Phe--Phe(p-NO 2)--OH,--Trp--Phe(p-NO 2)--H or--Phe--Trp--NH 2.
