146398-01-8

Basic information

• Product Name: (R)-4-hydroxy-2-{[(phenylmethoxy)carbonyl]amino}butanoic acid 1,1-dimethylethyl ester
• Synonyms: (R)-4-hydroxy-2-{[(phenylmethoxy)carbonyl]amino}butanoic acid 1,1-dimethylethyl ester
• CAS NO: 146398-01-8
• Molecular Weight: 309.362
• Mol File: 146398-01-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-4-hydroxy-2-{[(phenylmethoxy)carbonyl]amino}butanoic acid 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-hydroxy-2-{[(phenylmethoxy)carbonyl]amino}butanoic acid 1,1-dimethylethyl ester(146398-01-8)
• EPA Substance Registry System: (R)-4-hydroxy-2-{[(phenylmethoxy)carbonyl]amino}butanoic acid 1,1-dimethylethyl ester(146398-01-8)

Safety Data

• Hazardous Substances Data: 146398-01-8(Hazardous Substances Data)

Upstream product

• 71449-08-6 (2R)-2-{[(benzyloxy)carbonyl]amino}-4-tert-butoxy-4-oxobutanoic acid 

Downstream Products

• 1022975-13-8 (R)-4-oxo-3-{[(phenylmethoxy)carbonyl]amino}butanoic acid 1,1-dimethylethyl ester 
• 146398-15-4 (S)-tert-butyl 3-<(benzyloxycarbonyl)amino>-5-methylhexanoate 
• 146398-05-2 tert-butyl 3-<(benzyloxycarbonyl)amino>-4-iodobutanoate 
• 118247-68-0 N-Benzyloxycarbonyl-L-Homoleucine 
• 147395-39-9 Ac-Tyr-Val-Ala-D-Asp(O^tBu)-H dimethyl acetal 
• 426254-23-1 (-)-tert-butyl (S)-N-(benzyloxycarbonyl)-3-aminobutanoate 
• 441298-10-8 (2R,3S)-2-[4-(2-Methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-1,3-dicarboxylic acid di-tert-butyl ester 
• 761435-53-4 (S)-2-[(R)-2-(4-Benzyloxy-benzenesulfonyl)-1-benzyloxycarbonylamino-ethyl]-5-hydroxy-pentanoic acid tert-butyl ester 
• 441298-16-4 (2R,3S)-2-[4-(2-Methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-pyrrolidine-1,3-dicarboxylic acid di-tert-butyl ester 
• 761435-51-2 (S)-2-[(R)-2-(4-Benzyloxy-benzenesulfonyl)-1-benzyloxycarbonylamino-ethyl]-pent-4-enoic acid tert-butyl ester 
• 761435-55-6 (S)-2-[(R)-2-(4-Benzyloxy-benzenesulfonyl)-1-benzyloxycarbonylamino-ethyl]-5-oxo-pentanoic acid tert-butyl ester 
• 761435-72-7 (2S,3R)-4-(4-Benzyloxy-benzenesulfonyl)-3-benzyloxycarbonylamino-2-(2-oxo-ethyl)-butyric acid tert-butyl ester 
• 761435-49-8 (S)-2-[(R)-1-Benzyloxycarbonylamino-2-(4-benzyloxy-phenylsulfanyl)-ethyl]-pent-4-enoic acid tert-butyl ester 
• 761435-47-6 3-benzyloxycarbonylamino-4-(4-benzyloxy-phenylsulfanyl)-butyric acid tert-butyl ester 

Relevant articles and documents

Synthesis method of (R)-tert-butyl 4-hydroxy-1-methoxybut-2-ylcarbamate

The invention belongs to the field of organic synthesis, and discloses a synthesis method of (R)-tert-butyl 4-hydroxy-1-methoxybut-2-ylcarbamate. The synthesis method disclosed by the invention comprises the following steps: (A) reacting a compound 1 with

Synthesis and evaluation of enantiomeric purity of protected α-amino and peptide aldehydes

The synthesis of enantiomerically pure Ac-Tyr-Val-Ala-Asp(O'Bu)-H dimethyl acetal ((S)-1) is reported, a protected tetrapeptide C-terminal aldehyde belonging to a class of potent, reversible inhibitors of cysteine proteases (e.g., interleukin-1β-convertin