146422-72-2Relevant articles and documents
Design, Synthesis, and Neurochemical Evaluation of 5-(3-Alkyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidines as M1 Muscarinic Receptor Agonists
Dunbar, Philip G.,Durant, Graham J.,Fang, Zheng,Abuh, Yahaya F.,El-Assadi, Afif A.,et al.
, p. 842 - 847 (2007/10/02)
A series of 5-(3-alkyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidines (7a-h) was synthesized for biological evaluation as selective agonists for M1 receptors coupled to phosphoinositide (PI) metabolism in the central nervous system.Each li