146432-73-7Relevant articles and documents
Synthesis of indolizine-5,8-diones and [3.2.2]cyclazines
Yerxa, Benjamin R.,Moore, Harold W.
, p. 7811 - 7814 (2007/10/02)
The thermally induced ring expansion of 4-(1-pyrrolyl)-4-trimethylsiloxycyclobutenones to 5-hydroxy-8-trimethylsiloxyindolizines and their subsequent oxidation to the rare indolizine-5,8-diones is described. When the rearrangement is carried out in the presence of DMAD the indolizines are trapped in an 8+2 cycloaddition to give [3.2.2]cyclazines.