146479-72-3

Basic information

• Product Name: Follicle-stimulating hormone
• Synonyms: FOLLICLE STIMULATING HORMONE;Follicle-stimulating hormone (human A-subunit reduced), complex with follicle-stimulating hormone (human B-subunit reduced);Follicle-stimulating hormone, glycoform b;Follistim;Follistim aq;Follistim-aq;Follistim-aq cartridge;Follitropin beta
• CAS NO: 146479-72-3
• Molecular Formula: C42H65N11O12S2
• Molecular Weight: 980.162
• EINECS: 232-681-7
• Mol File: 146479-72-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Follicle-stimulating hormone(CAS DataBase Reference)
• NIST Chemistry Reference: Follicle-stimulating hormone(146479-72-3)
• EPA Substance Registry System: Follicle-stimulating hormone(146479-72-3)

Safety Data

• Hazardous Substances Data: 146479-72-3(Hazardous Substances Data)

Usage

Description

Follicle-stimulating hormone (FSH), also known as Follitropin beta, is a hormone of recombinant DNA origin that is chemically similar to natural FSH and follitropin alfa, with only slight differences in the composition of the carbohydrate side chains. The primary and tertiary structures of both follitropins alfa and beta are indistinguishable from those of naturally occurring human FSH. Bioassays and physiochemical studies have shown that follitropins alfa and beta are also indistinguishable from each other.

Uses

Used in Reproductive Medicine:
Follicle-stimulating hormone is used as a therapeutic agent for the treatment of infertility in women. It stimulates the growth and maturation of ovarian follicles, which can help increase the chances of successful conception.
Used in Assisted Reproductive Technology (ART):
FSH is used as a key component in the process of in vitro fertilization (IVF) and other assisted reproductive technologies. It is administered to stimulate the development of multiple ovarian follicles, which can then be retrieved and fertilized in a laboratory setting.
Used in Male Infertility Treatment:
Follicle-stimulating hormone is also used in the treatment of male infertility, particularly in cases where low sperm count or poor sperm quality is due to hormonal imbalances. It can help stimulate sperm production by promoting the development of sperm cells within the testes.
Used in Research and Development:
FSH, specifically follitropin beta, is used in various research and development applications, such as studying the effects of FSH on follicular development, understanding the role of FSH in reproductive health, and developing new treatments for infertility and other related conditions.