146560-54-5Relevant articles and documents
SYNTHESIS AND BIOLOGICAL ACTIVITY OF NOVEL N-1-ARYL-6-FLUORO-5-METHYL-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS
Jacquet, Jean-Pierre,Bouzard, Daniel,Cesare, Pierre Di,Dolnic, Nicolas,Massoudi, Massoud,Remuzon, Philippe
, p. 2301 - 2311 (2007/10/02)
A series of 5-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acids was prepared in which the N-1 position was substituted by various aryl groups.Seven compounds showed excellent in vitro antibacterial activity against Gram-positive and Gram-negative strains.