14660-20-9Relevant articles and documents
Synthesis of 5-Membered Sulfur Heterocycles via Tin-Catalyzed Annulation of Mercapto Ketones with Activated Alkenes
Suzuki, Itaru,Sakamoto, Yuki,Seo, Yuta,Ninomaru, Yoriko,Tokuda, Kodai,Shibata, Ikuya
, p. 2759 - 2769 (2020)
Efficient conversion of α-mercapto ketones 1 with activated alkenes 2 into S-heterocycles was developed with Sn(Oct)2-2MeOH acting as a catalyst. Two types of products, dihydrothiophene 3 and thiolane 4, were obtained. The selectivity of the products was dependent on the reaction temperature and on the rearrangement of the S-heterocycles from 3 to 4 under heating conditions. The dihydrothiophenes 3 were transformed into useful thiolactones 6-8 and thiophene 9.
Synthesis of β-Thioxoketones by t-Butyllithium-Promoted Claisen Condensation Reaction of Ketones with Thionoesters
Duus, Fritz
, p. 672 - 674 (2007/10/02)
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