146713-21-5

Basic information

• Product Name: N-[9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-(2-cyano-ethylsulfanyl)-9H-purin-2-yl]-2,2,2-trifluoro-acetamide
• Synonyms: N-[9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-(2-cyano-ethylsulfanyl)-9H-purin-2-yl]-2,2,2-trifluoro-acetamide
• CAS NO: 146713-21-5
• Molecular Weight: 734.756
• Mol File: 146713-21-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-(2-cyano-ethylsulfanyl)-9H-purin-2-yl]-2,2,2-trifluoro-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-(2-cyano-ethylsulfanyl)-9H-purin-2-yl]-2,2,2-trifluoro-acetamide(146713-21-5)
• EPA Substance Registry System: N-[9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-(2-cyano-ethylsulfanyl)-9H-purin-2-yl]-2,2,2-trifluoro-acetamide(146713-21-5)

Safety Data

• Hazardous Substances Data: 146713-21-5(Hazardous Substances Data)

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 146691-58-9 S⁶-cyanoethyl-N²-trifluoroacetyl-2'-deoxy-6-thioguanoside 

Downstream Products

• 146691-59-0 Diisopropyl-phosphoramidous acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-[6-(2-cyano-ethylsulfanyl)-2-(2,2,2-trifluoro-acetylamino)-purin-9-yl]-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester 

Relevant articles and documents

A novel synthesis of S6-cyanoethyl-2'-deoxy-6-thioguanosine and its incorporation into triple helix forming oligonucleotides

A simple and expeditious synthesis of S6-cyanoethyl-2'-deoxy-6-thioguanosine from 2'-deoxyguanosine has been accomplished in good yield and incorporated into several triple helix forming oligonucleotides using the solid-phase phosphoramidite ch