146773-32-2Relevant articles and documents
COMPOUNDS AND USES THEREOF
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Page/Page column 137; 179, (2021/10/15)
The present disclosure features compounds useful for the treatment of BAF complex-related disorders.
HDAC DEGRADER
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Page/Page column 37-38; 46-47, (2021/07/31)
The disclosure provides compounds of formula (I). The compounds may be used to degrade the Histone Deacetylase (HDAC) family of enzymes, particularly HDAC1, 2 and 3 that exist in corepressor complexes. Accordingly, the compounds may
Novel tumor-targeted RGD peptide-camptothecin conjugates: Synthesis and biological evaluation
Dal Pozzo, Alma,Ni, Ming-Hong,Esposito, Emiliano,Dallavalle, Sabrina,Musso, Loana,Bargiotti, Alberto,Pisano, Claudio,Vesci, Loredana,Bucci, Federica,Castorina, Massimo,Fodera, Rosanna,Giannini, Giuseppe,Aulicino, Concetta,Penco, Sergio
experimental part, p. 64 - 72 (2010/04/06)
Five RGD peptide-camptothecin (CPT) conjugates were designed and synthesized with the purpose to improve the therapeutic index of this antitumoral drug family. New RGD cyclopeptides were selected on the basis of their high affinity to αv integr
