146828-51-5Relevant articles and documents
4-Hydroxy-2-quinolones. 4. Selection of the Optimum Path for the Synthesis of N-R-Substituted 4-Hydroxy-2-quinolone-3-carboxylic Acid Amides
Ukrainets, I. V.,Bezuglyi, P. A.,Treskach, V. I.,Turov, A. V.
, p. 538 - 540 (1992)
A comparison of several methods of preparation of N-R-substituted 4-hydroxy-2-quinolone-3-carboxylic acid amides showed that intramolecular cyclization of 2-carbalkoxymalonanilic acid ethyl esters with simultaneous amidation is the most rational method.