14684-31-2

Basic information

• Product Name: Phosphinic acid, methyl ester
• Synonyms: Phosphinic acid,methyl ester;Phosphinigsaeuremethylester;methyl phosphinate;methyl hypophosphite
• CAS NO: 14684-31-2
• Molecular Formula: CH5O2P
• Molecular Weight: 80.0233
• Mol File: 14684-31-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phosphinic acid, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphinic acid, methyl ester(14684-31-2)
• EPA Substance Registry System: Phosphinic acid, methyl ester(14684-31-2)

Safety Data

• Hazardous Substances Data: 14684-31-2(Hazardous Substances Data)

Upstream product

• 149-73-5 trimethyl orthoformate 

Downstream Products

• 146406-49-7 methyl bis(4-nitrophenyl)phosphinate 
• 146406-44-2 methyl 4-nitrophenylphosphinate 
• 146406-47-5 methyl (4-methylphenyl)-4-(phenylphenyl)phosphinate 
• 13336-55-5 methyl 4-methylphenylphosphinate 
• 83470-30-8 methyl bis-(4-methylphenyl)phosphinate 
• 146406-43-1 methyl 4-hydroxyphenylphosphinate 
• 146406-45-3 methyl 2-(methoxycarbonyl)phenylphosphinate 
• 146406-48-6 methyl (4-<2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)ethyl>phenyl) <4-(ethoxycarbonyl)phenyl>phosphinate 
• 146406-46-4 (S)-2-tert-Butoxycarbonylamino-3-(4-{[4-((S)-2-tert-butoxycarbonylamino-2-methoxycarbonyl-ethyl)-phenyl]-methoxy-phosphinoyl}-phenyl)-propionic acid methyl ester 
• 158686-45-4 (S)-2-tert-Butoxycarbonylamino-3-(4-methoxyphosphinoyl-phenyl)-propionic acid methyl ester 
• 146406-46-4 methyl bis(4-<2-(tert-butoxycarbonylamino)-2-(methyloxycarbonyl)ethyl>phenyl)phosphinate 
• 250782-63-9 (S,S)-methyl di(1-acetyloxy-3-phenyl-2E-propenyl)phosphinate 
• 250782-61-7 (S,S)-methyl di[1-acetyloxy-1-(4-methylphenyl)methyl]phosphinate 
• 250782-62-8 (S,S)-methyl di[1-acetyloxy-1-(4-chlorophenyl)methyl]phosphinate 

Relevant articles and documents

Preparation of phosphinodipeptide analogs as building blocks for pseudopeptides synthesis

A simple and effective preparation of phosphinodipeptides, in good overall yields, has been developed. This one pot procedure, allowing the variation of the substituents in α and/or β position to the phosphorus atom and also in α position to the nitrogen atom, consists in the addition of alkyl hypophosphites to imines, followed by Michael-addition on acrylates. To show the value of phosphinodipeptides analogs 1 as synthetic intermediates, selective deprotections of the three functional groups are described.