14686-89-6 Usage
Description
DIACETONE-D-GLUCOSE, also known as 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose, is an off-white crystalline solid with unique chemical properties. It is a derivative of glucose, a simple sugar, and is commonly used in various applications due to its reactivity and structural characteristics.
Uses
Used in Chemical Synthesis:
DIACETONE-D-GLUCOSE is used as a reagent for the preparation of fluorinated UDP-galactofuranose probes. These probes are essential in the study of various biological processes and the development of new pharmaceutical compounds.
Used in Pharmaceutical Industry:
DIACETONE-D-GLUCOSE is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of novel molecules with potential therapeutic applications.
Used in Research and Development:
DIACETONE-D-GLUCOSE is used as a research tool in the development of new chemical processes and methodologies. Its reactivity and structural properties make it a valuable asset in the advancement of scientific knowledge.
Used in Analytical Chemistry:
DIACETONE-D-GLUCOSE can be employed as a reference compound or standard in analytical chemistry, helping to calibrate instruments and ensure the accuracy of experimental results.
Check Digit Verification of cas no
The CAS Registry Mumber 14686-89-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,6,8 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 14686-89:
(7*1)+(6*4)+(5*6)+(4*8)+(3*6)+(2*8)+(1*9)=136
136 % 10 = 6
So 14686-89-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H20O6/c1-11(2)14-5-6(16-11)8-7(13)9-10(15-8)18-12(3,4)17-9/h6-10,13H,5H2,1-4H3/t6-,7+,8-,9-,10-/m1/s1
14686-89-6Relevant articles and documents
Triethylamine-methanol mediated selective removal of oxophenylacetyl ester in saccharides
Rasool, Javeed Ur,Kumar, Atul,Ali, Asif,Ahmed, Qazi Naveed
, p. 338 - 347 (2021/01/29)
A highly selective, mild, and efficient method for the cleavage of oxophenylacetyl ester protected saccharides was developed using triethylamine in methanol at room temperature. The reagent proved successful against different labile groups like acetal, ketal, and PMB and also generated good yields of the desired saccharides bearing lipid esters. Further, we also observed DBU in methanol as an alternative reagent for the deprotection of acetyl, benzoyl, and oxophenylacetyl ester groups. This journal is
Larger laboratory scale synthesis of 5-methyluridine and formal synthesis of its L-enantiomer
Thiesen, Luciano J. Hoeltgebaum,Cabral, Nadia,Joselice E Silva, Maria,Bezerra, Gilson,Doboszewski, Bogdan
, p. 249 - 264 (2017/06/19)
A larger laboratory scale synthesis (>60 g per run) of 5-methyluridine is presented. The critical intermediate 1,2-O-isopropylidene-α-D-ribofuranose was prepared from very cheap D-glucose via D-allose. Its L-enantiomer was obtained from L-arabinose via L-glucose, and also from L-xylose. {figure presented}.
Synthesis of a MUC1-glycopeptide-BSA conjugate vaccine bearing the 3′-deoxy-3′-fluoro-Thomsen-Friedenreich antigen
Hoffmann-Roeder, Anja,Johannes, Manuel
supporting information; experimental part, p. 9903 - 9905 (2011/10/09)
A novel MUC1-glycopeptide-BSA conjugate vaccine with a specifically fluorinated Thomsen-Friedenreich antigen side chain at Thr6 was prepared. Preliminary immunological experiments reveal specific binding of the tumor-associated glycopeptide antigen analog by anti-MUC1-mouse antibodies.