14688-28-9 Usage
Description
(3,5-diphenyl-1,2-oxazol-4-yl)(phenyl)methanone is a ketone derivative belonging to the oxazole family, characterized by a molecular formula of C25H19NO. It features a benzene ring with both a phenyl and an oxazol-4-yl group substitution, which contributes to its diverse chemical reactivity and potential biological activity. (3,5-diphenyl-1,2-oxazol-4-yl)(phenyl)methanone is a valuable building block in organic synthesis and pharmaceutical research, offering a wide range of applications due to its specific properties.
Uses
Used in Organic Synthesis:
(3,5-diphenyl-1,2-oxazol-4-yl)(phenyl)methanone is used as a key intermediate in organic synthesis for the creation of various complex organic molecules. Its unique structure allows for multiple points of reactivity, making it suitable for the synthesis of a broad range of compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (3,5-diphenyl-1,2-oxazol-4-yl)(phenyl)methanone is utilized as a starting material for the development of new medications. Its potential biological activity and chemical versatility make it an attractive candidate for the design and synthesis of novel drug molecules targeting various therapeutic areas.
Used in Medicinal Chemistry:
(3,5-diphenyl-1,2-oxazol-4-yl)(phenyl)methanone serves as a valuable building block in medicinal chemistry, where it can be used to construct and optimize the structure of drug candidates. Its presence in a molecule can influence pharmacokinetic and pharmacodynamic properties, contributing to the overall effectiveness and safety of potential drugs.
Used in Chemical Research:
(3,5-diphenyl-1,2-oxazol-4-yl)(phenyl)methanone is also employed in chemical research to study the reactivity and properties of oxazole-containing molecules. Understanding its behavior in various chemical reactions can provide insights into the development of new synthetic methods and the discovery of new chemical entities with useful applications.
Check Digit Verification of cas no
The CAS Registry Mumber 14688-28-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,6,8 and 8 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 14688-28:
(7*1)+(6*4)+(5*6)+(4*8)+(3*8)+(2*2)+(1*8)=129
129 % 10 = 9
So 14688-28-9 is a valid CAS Registry Number.
14688-28-9Relevant articles and documents
Enolate-mediated 1,3-dipolar cycloaddition reaction of β-functionalized ketones with nitrile oxides: Direct access to 3,4,5-trisubstituted isoxazoles
Zhou, Xiao,Xu, Xianhong,Shi, Zhenyan,Liu, Kun,Gao, Hua,Li, Wenjun
supporting information, p. 5246 - 5250 (2016/07/06)
TMG-catalyzed [3 + 2] organocatalytic 1,3-dipolar cycloaddition reactions of β-functionalized ketones with nitrile oxides have been developed. This strategy could generate 3,4,5-trisubstituted isoxazoles in high yields and regioselectivities.
Formation of 4-Benzamidoisoxazole Derivatives
Zen, Shonosuke,Harada, Kazuho,Nakamura, Hikaru,Iitaka, Yoichi
, p. 2881 - 2884 (2007/10/02)
The titled compounds (3) were synthesized by the reaction of nitrile oxides with 1-azirines and also the reaction of aliphatic nitro compounds with dibenzoylmethane derivatives in the presence of acetyl chloride and sodium methoxide.The structure of 3 was
Regioselectivity in the Reactions of Benzonitrile N-Phenylimide and Some Benzonitrile N-Oxides with α,β-Unsaturated Ketones
Bianchi, Giorgio,Gandolfi, Remo,Micheli, Carlo De
, p. 135 - 158 (2007/10/02)
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