146900-33-6Relevant articles and documents
Synthesis and phosphorylating properties of hydroxyamino acid phosphoramidites
Dreef-Tromp,Lefeber,Van Der Marel,Van Boom
, p. 1269 - 1272 (2007/10/02)
The preparation of N-(benzyloxycarbonyl)-O-[(benzyloxy)(diisopropylamino)phosphino]serine [-threonine, -tyrosine and -hydroxyproline] benzyl esters using the versatile phosphitylating reagent benzyl N,N,N',N'-tetraisopropylphosphorodiamidite [benzyloxybis(diisopropylamino)phosphine] is described. The application of the benzyl (hydroxyamino acid) phosphoramidites is illustrated in the synthesis of several phosphate diesters.