147-84-2 Usage
Description
DIETHANOL-DITHIOCARBAMATE, also known as N,N-Diethyldithiocarbamic Acid, is a metabolite of Disulfiram (D493640). It is a compound with the ability to inhibit superoxide dismutase, which plays a crucial role in the regulation of cellular oxidative processes. DIETHANOL-DITHIOCARBAMATE has the potential to either potentiate or protect against cell oxidative damage caused by ionizing radiation, making it a compound of interest in various applications.
Uses
Used in Pharmaceutical Applications:
DIETHANOL-DITHIOCARBAMATE is used as an inhibitor of superoxide dismutase for its potential to modulate cellular oxidative processes. This application is particularly relevant in the context of cell oxidative damage caused by ionizing radiation, where DIETHANOL-DITHIOCARBAMATE can either potentiate or protect against such damage, depending on the specific context and desired outcome.
Used in Radiation Protection:
In the field of radiation protection, DIETHANOL-DITHIOCARBAMATE is used as a protective agent against cell oxidative damage caused by ionizing radiation. Its ability to inhibit superoxide dismutase makes it a valuable compound for research and potential therapeutic applications in scenarios involving exposure to ionizing radiation, such as cancer treatment or occupational exposure in certain industries.
Used in Research Applications:
DIETHANOL-DITHIOCARBAMATE is also used as a research tool in the study of superoxide dismutase and its role in cellular oxidative processes. By inhibiting this enzyme, researchers can gain insights into the underlying mechanisms of oxidative stress and potential strategies for mitigating its harmful effects.
Check Digit Verification of cas no
The CAS Registry Mumber 147-84-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 147-84:
(5*1)+(4*4)+(3*7)+(2*8)+(1*4)=62
62 % 10 = 2
So 147-84-2 is a valid CAS Registry Number.
InChI:InChI=1/C5H11NS2.K/c1-3-6(4-2)5(7)8;/h3-4H2,1-2H3,(H,7,8);/q;+1/p-1
147-84-2Relevant articles and documents
Choukroun,Gervais
, p. 163 (1978)
Synthesis of S- and N-functionalized dithiocarbamates from cyclic sulfates
Parada-Aliste, Jose,Megia-Fernandez, Alicia,De La Torre-Gonzalez, Diego,Hernandez-Mateo, Fernando,Santoyo-Gonzalez, Francisco
, p. 3758 - 3763 (2013)
A novel methodology for the synthesis of S- and N-functionalized dithiocarbamates starting from cyclic sulfates, amines and carbon disulfide by using different protocols, including microwave assistance and a multicomponent variant, has been developed. The procedure is highly versatile, simple and efficient. As an efficient route to dithiocarbamates, a simple and versatile method for preparing S- and N-functionalized dithiocarbamates starting for readily available cyclic sulfates and commercial amines under environmentally friendly conditions is reported. Copyright
Visible-Light-Induced Photocatalytic Synthesis of β-Keto Dithiocarbamates via Difunctionalization of Styrenes
Vishwakarma, Ramesh Kumar,Kumar, Saurabh,Singh, Krishna Nand
supporting information, p. 4147 - 4151 (2021/05/26)
A facile photocatalyzed strategy for difunctionalization of styrenes in the presence of CS2 and amines providing β-keto dithiocarbamates has been developed. In the case of 4-nitrostyrene and 2-vinylpyridine, however, only 2-arylethylthiocarbamates are interestingly formed without the aid of photoredox catalysis/TBHP.
PROCHELATORS AS TARGETED PRODRUGS FOR PROSTATE CANCER AND METHODS OF MAKING AND USING SAME
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Paragraph 00219-00221, (2019/01/21)
The present disclosure provides prochelators as targeted prodrugs for cancer, such as prostate cancer, and methods of making and using the same.
