147106-99-8

Basic information

• Product Name: [2-(3-bromo-propoxy)-phenyl]-acetic acid methyl ester
• Synonyms: [2-(3-bromo-propoxy)-phenyl]-acetic acid methyl ester
• CAS NO: 147106-99-8
• Molecular Weight: 287.153
• Mol File: 147106-99-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [2-(3-bromo-propoxy)-phenyl]-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(3-bromo-propoxy)-phenyl]-acetic acid methyl ester(147106-99-8)
• EPA Substance Registry System: [2-(3-bromo-propoxy)-phenyl]-acetic acid methyl ester(147106-99-8)

Safety Data

• Hazardous Substances Data: 147106-99-8(Hazardous Substances Data)

Upstream product

• 22446-37-3 methyl (2-hydroxyphenyl)acetate 
• 109-64-8 1,3-dibromo-propane 

Downstream Products

• 787619-54-9 [2-(3-Morpholin-4-yl-propoxy)-phenyl]-acetic acid methyl ester 
• 185802-89-5 [2-(3-Bromo-propoxy)-phenyl]-acetic acid 

Relevant articles and documents

PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease

The invention provides compounds of Formula (I) the stereoisomers and prodrugs thereof, and the pharmaceutically acceptable salts of the compounds, stereoisomers, and prodrugs, wherein A, P, J, x, and R10 are as defined herein; pharmaceutical compositions thereof; and methods of using the pharmaceutical compositions for the treatment of diseases, including, diabetes, including type 1 and type 2 diabetes, hyperglycemia, dyslipidemia, impaired glucose tolerance, metabolic syndrome, and/or cardiovascular disease.

Perhydroisoindole derivatives and pharmaceutical compositions containing them

This invention relates to derivatives of perhydroisoindol of formula: STR1 in which the radicals R are hydrogen atoms or together form a bond, the symbols R' are phenyl radicals which can be substituted by a halogen atom or a methyl radical in position 2 or 3, X is an oxygen atom or an NH radical, R1 is optionally substituted phenyl, or cyclohexadienyl, naphthyl, or heterocyclyl, R2 is H, halogen, OH, alkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkyloxy, alkylthio, acyloxy, carboxy, optionally substituted alkyloxycarbonyl, benzyloxycarbonyl, amino or acylamino, R3 is halogen or OH and R4 is H or halogen if R3 is halogen, in their isomer forms, or mixture thereof, and possibly also their salts when they exist, and preparation thereof. The derivatives of the invention are particularly interesting as P substance antagonist.