14731-29-4Relevant articles and documents
Synthesis and evaluation of new 1,3,4-thiadiazole derivatives as potent antifungal agents
Karaburun, Ahmet ?agr?,?evik, Ulviye Acar,Osmaniye, Derya,Sagl?k, Begüm Nurpelin,?avu?oglu, Betül Kaya,Levent, Serkan,?zkay, Yusuf,Koparal, Ali Sava?,Beh?et, Mustafa,As?m Kaplanc?kl?, Zafer
, (2018)
With the goal of obtaining a novel bioactive compound with significant antifungal activity, a series of 1,3,4-thiadiazole derivatives (3a–3l) were synthesized and characterized. Due to thione-thiol tautomerism in the intermediate compound 2, type of subst
an interesting isomerization: synthesis of mesoionic 5-arylamino-1,3,4-thiadiazolium-2-thiolates by using ω-bromo-ω-(1H-1,2,4-triazol-1-yl)acetophenone as catalyst
Chu, Chang-Hu,Hui, Xin-Ping,Xu, Peng-Fei,Zhang, Zi-Yi,Li, Zhi-Chun,Liao, Ren-An
, p. 943 - 946 (2007/10/03)
Mesoionic 5-arylamino-1,3,4-thiadiazolium-2-thiolates 7a-f were prepared by the isomerization of 5-arylamino-1,3,4-thiadiazol-2-thiones 5a-f by using ω-bromo-ω-(1H-1,2,4-triazol-1-yl)acetophenone 6 as catalyst. All the structures of mesoionic synthesized were confirmed by elemental analyses, 1H NMR, IR and MS spectral data. We have also determined the x-ray photoelectron spectroscopy (XPS) of the mesoionic and their precursors. A comparison of XPS spectra between the mesoionic and their precursors showed that the charge separation in mesoionic is distinctly larger than in their precursors.