147349-28-8

Basic information

• Product Name: (2S,3S)-2,3-EPOXY-3-PHENYLPROPYL 4-NITROPHENYL CARBONATE
• Synonyms: (2S,3S)-TRANS-3-PHENYL-2-OXIRANYLMETHYL-4-NITROPHENYL CARBONATE;(2S,3S)-2,3-EPOXY-3-PHENYLPROPYL 4-NITROPHENYL CARBONATE;4-NITROPHENYL-(2S,3S)-2,3-EPOXY-3-PHENYLPROPYL CARBONATE;(S)-NEPC;(2S,3S)-TRANS-3-PHENYL-2-OXIRANYLMETHYL- 4-NITROPHE CARBONAT;(2S,3S)-2,3-Epoxy-3-phenylpropyl 4-nitrophenyl carbonate, (S)-NEPC, 4-Nitrophenyl (2S,3S)-2,3-epoxy-3-phenylpropyl carbonate;S-NEPC Exclusive;NIEXHSMFFPOGRX-GJZGRUSLSA-N
• CAS NO: 147349-28-8
• Molecular Formula: C16H13NO6
• Molecular Weight: 315.28
• Mol File: 147349-28-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 69-72 °C
• Boiling Point: 494.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.372±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (2S,3S)-2,3-EPOXY-3-PHENYLPROPYL 4-NITROPHENYL CARBONATE(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-2,3-EPOXY-3-PHENYLPROPYL 4-NITROPHENYL CARBONATE(147349-28-8)
• EPA Substance Registry System: (2S,3S)-2,3-EPOXY-3-PHENYLPROPYL 4-NITROPHENYL CARBONATE(147349-28-8)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 4.3-10
• Hazardous Substances Data: 147349-28-8(Hazardous Substances Data)

Usage

Description

(2S,3S)-2,3-EPOXY-3-PHENYLPROPYL 4-NITROPHENYL CARBONATE is a chiral epoxide derivative with the molecular formula C15H13NO6. It is commonly used as a reagent in organic synthesis due to its ability to act as an efficient catalyst in asymmetric Michael additions. (2S,3S)-2,3-EPOXY-3-PHENYLPROPYL 4-NITROPHENYL CARBONATE is also useful in the synthesis of various pharmaceuticals and natural products, as well as in the protection and deprotection of alcohol functional groups in organic synthesis.

Uses

Used in Organic Synthesis:
(2S,3S)-2,3-EPOXY-3-PHENYLPROPYL 4-NITROPHENYL CARBONATE is used as a reagent in organic synthesis for its ability to act as an efficient catalyst in asymmetric Michael additions. This allows for the selective formation of specific products in chemical reactions, which is important for the synthesis of complex molecules.
Used in Pharmaceutical and Natural Product Synthesis:
(2S,3S)-2,3-EPOXY-3-PHENYLPROPYL 4-NITROPHENYL CARBONATE is used in the synthesis of various pharmaceuticals and natural products. Its unique structure and reactivity make it a valuable building block for the development of new drugs and other bioactive compounds.
Used in Alcohol Protection and Deprotection:
(2S,3S)-2,3-EPOXY-3-PHENYLPROPYL 4-NITROPHENYL CARBONATE is used as a protecting group for alcohols in organic synthesis. The 4-nitrophenyl carbonate group can be easily removed under mild conditions, making this compound useful for the protection and deprotection of alcohol functional groups during chemical reactions.
Used in Chemical Reactions with Steric Hindrance:
The phenylpropyl group in (2S,3S)-2,3-EPOXY-3-PHENYLPROPYL 4-NITROPHENYL CARBONATE adds steric hindrance, which may influence the reactivity and selectivity of the compound in various chemical reactions. This can be useful in controlling the outcome of reactions and improving the yield of desired products.