147365-19-3Relevant articles and documents
Small molecular gelling agents to harden organic liquids: Trialkyl cis-1,3,5-cyclohexanetricarboxamides
Hanabusa, Kenji,Kawakami, Atsushi,Kimura, Mutsumi,Shirai, Hirofusa
, p. 191 - 192 (1997)
Trialkyl cis-1,3,5-cyclohexanetricarboxamides were able to cause physical gelation in organic liquids to afford completely transparent organogel. The main driving force for gelation was intermolecular hydrogen bonding between amides and van der Waals inte
A flexible solution to anion transport: Powerful anionophores based on a cyclohexane scaffold
Cooper, James A.,Street, Steven T. G.,Davis, Anthony P.
, p. 5609 - 5613 (2014)
Transmembrane anion carriers (anionophores) have potential for biological activity, including the treatment of channelopathies such as cystic fibrosis. A new family of anionophores has been synthesized, in which three thiourea groups are mounted on a cyclohexane-based scaffold. Though conceptually related to earlier polycyclic systems, these molecules are simpler and far more accessible. Preorganization is somewhat reduced compared to earlier systems, and anion affinities are correspondingly lower. However, transport activities set new records. This surprising performance suggests a role for controlled flexibility in the design of transmembrane anion carriers. Speedy shuttling: New anionophores were developed which are simpler and far more accessible than conceptually related earlier systems. They are also less preorganized and anion affinities are lower (as expected), but transport activities set new records. This surprising performance suggests a role for controlled flexibility in the design of transmembrane anion carriers.
SOLVENT COMPOSITION FOR ELECTRONIC DEVICE PRODUCTION
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Paragraph 0074-0077, (2021/04/23)
The present invention provides a solvent composition for use in an ink for producing an electronic device using a printing method, the solvent composition being capable of improving the printing accuracy of the ink, being fired at low temperatures, and su
A multi-step continuous (1 α, 3 α, 5 α) - 1, 3, 5 - [...] preparation method
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Paragraph 0064; 0075, (2019/04/04)
The present invention discloses a multi-step continuous (1 α, 3 α, 5 α) - 1, 3, 5 - [...] preparation method. The invention provides a multi-step continuous (1 α, 3 α, 5 α) - 1, 3, 5 - [...] preparation method, comprising the following steps: (1) in a solvent, in the presence of an organic base, the compound 2 with phenol to carry out the esterification reaction, to obtain compound 3 of the reaction solution can be; (2) the step (1) the obtained containing compound 3 of reaction liquid and ammonia gas to ammonolysis reaction, to obtain compound 4 can be. The method raw materials are cheap, simple and convenient operation, high yield, the product quality is good, few by-products at the same time, omit the after-processing, the generated three waste a significant reduction of the and the like, and is suitable for industrial production.
Remarkable solvent isotope dependence on gelation strength in low molecular weight hydro-gelators
Canrinus, Tjalling R.,Cerpentier, Florian J. R.,Feringa, Ben L.,Browne, Wesley R.
supporting information, p. 1719 - 1722 (2017/02/10)
A delicate interplay of anisotropic hydrophobic/hydrophilic, π-π stacking, ionic and hydrogen bond interactions determine the strength of hydrogelators and are considered key factors in efforts to design potent small molecule hydrogelators. Here we show that solvent deuteration and electrolytic strength affect the strength of hydrogels formed from amino acid modified C3-symmetric cyclohexane trisamides profoundly. Gels formed by self-assembly through heating/cooling of solutions or by pH switching show up to a 30 °C increase in their melting temperatures in D2O compared to H2O. The unusually large solvent isotope effect on gel formation and thermal properties indicates that, in contrast to expectations, hydrogen bonding is not the primary determinant of gel strength but instead that hydrophobic interactions between the gelator molecules and the terminal carboxylic acid units are of greater importance. A conclusion that is supported by a similarly large effect of electrolytes on gel strength.
