14737-94-1

Basic information

• Product Name: 2-Propenoic acid, 2-chloro-3-phenyl-, methyl ester, (E)-
• CAS NO: 14737-94-1
• Molecular Formula: C10H9ClO2
• Molecular Weight: 196.633
• Mol File: 14737-94-1.mol
• Article Data: 30

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 2-chloro-3-phenyl-, methyl ester, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 2-chloro-3-phenyl-, methyl ester, (E)-(14737-94-1)
• EPA Substance Registry System: 2-Propenoic acid, 2-chloro-3-phenyl-, methyl ester, (E)-(14737-94-1)

Safety Data

• Hazardous Substances Data: 14737-94-1(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Uses

Building block in synthesis of pharmaceuticals and chemical products, production of polymers, solvent in industrial processes

Health hazards

Skin and eye irritant, harmful if ingested or inhaled in large quantities

Safety precautions

Handle with caution, adhere to proper safety protocols when working with the chemical

Upstream product

• 103-26-4 Methyl cinnamate 
• 68-12-2 N,N-dimethyl-formamide 
• 705-55-5 (E)-2-chloro-3-phenylacrylic acid 
• 77-78-1 dimethyl sulfate 
• 186581-53-3 diazomethane 
• 16492-74-3 erythro-2,3-dichloro-3-phenylpropionic acid methyl ester 
• 16492-73-2 methyl erythro-3-acetoxy-2-chloro-3-phenylpropanoate 
• 20421-39-0 methyl erythro-2-chloro-3-fluoro-3-phenylpropanoate 
• 53910-20-6 methyl 2-(benzylthio)-2,2-dichloroacetate 
• 67-56-1 methanol 
• 74-88-4 methyl iodide 
• 4519-47-5 methyl 2-bromo-2-chloro-3-phenylpropanoate 
• 103-26-4 methyl cinnamate 
• 114642-84-1 methyl 3-bromo-2-chloro-3-phenylpropanoate 

Downstream Products

• 7474-06-8 (S)-2-chloro-3-phenyl-propionic acid 
• 59200-36-1 methyl (S)-2-chloro-3-phenylpropanoate 
• 1376213-31-8 (Z)-ethyl 4-chloro-3-oxo-5-phenylpent-4-enoate 
• 1376213-35-2 (Z)-propyl 4-chloro-3-oxo-5-phenylpent-4-enoate 
• 1376213-39-6 (Z)-methyl 4-chloro-3-oxo-5-phenylpent-4-enoate 
• 705-54-4 (Z)-α-chlorocinnamic acid 
• 705-55-5 (E)-2-chloro-3-phenylacrylic acid 
• 40235-35-6 methyl 5-phenyl-1H-1,2,3-triazole-4-carboxylate 
• 17193-31-6 (R,S)-2-amino-3-phenylpropionamide 
• 50290-43-2 4-phenyl-1,2-dihydropyrimido[1,2-a]benzimidazol-2-one 
• 79559-52-7 cis-2-phenylaziridine-3-carboxylic acid amide 
• 79559-52-7 trans-2-phenylaziridine-3-carboxylic acid amide 
• 74305-85-4 (Z)-2-chloro-3-phenylpropenoic acid amide 
• 79559-52-7 3-phenyl-aziridine-2-carboxylic acid amide 

Relevant articles and documents

Triethylamine-promoted elimination from (R,R)-PhCHORCHClCO2Me (R = MeCO, PhCO, 4-MeC6H4, 4-MeOC6H4, MeSO2 and 4-MeC6H4SO2) in various solvents

The rates and stereochemistry of elimination from a number of (R,R)- PhCHORCHClCO2Me (R = MeCO, PhCO, 4-MeC6H4, 4-MeOC6H4, MeSO2 and 4- MeC6H4SO2) with trie

Visible light-mediated metal-free double bond deuteration of substituted phenylalkenes

Various bromophenylalkenes were reductively photodebrominated by using 1,3-dimethyl-2-phenyl-1H-benzo-[d]imidazoline (DMBI) and 9,10-dicyanoanthracene. With deuterated DMBI analogs (the most effective was DMBI-d11), satisfactory to excellent isotopic yields were obtained. DMBI-d11 could also be regenerated from the reaction mixtures with a recovery rate of up to 50%. The combination of the photodebromination reaction with conventional methods for bromoalkene synthesis enables sequential monodeuteration of a double bond without the necessity of a metal catalyst. This journal is

Ru-catalyzed highly chemo- and enantioselective hydrogenation of γ-halo-γ,δ-unsaturated-β-keto esters under neutral conditions

Finely-tuned ruthenium-catalyzed highly chemoselective and enantioselective hydrogenation of γ-halo-γ,δ-unsaturated-β-keto esters at the carbonyl group was achieved under neutral reaction conditions (ee up to 97%). Both olefin and alkenyl halogen moieties, which are labile under hydrogenation conditions, remained untouched during the reaction.

Biocatalyzed enantioselective reduction of activated C=C bonds: Synthesis of enantiomerically enriched α-halo-β-arylpropionic acids

The enantioselective biocatalyzed reduction of the C=C bond of some (Z)-methyl α-halo-β-arylacrylates was investigated. The reaction was performed by baker's yeast fermentation and Old Yellow Enzymes 1-3 mediated biotransformations. The final products wer