1474-52-8Relevant articles and documents
Fishman,Guzik
, p. 2929 (1967)
-
David,Freud,de Jongh
, p. 1360,1363 (1934)
-
Tf2O-Promoted Trifluoromethythiolation of Various Arenes Using NaSO2CF3
Liu, Jie,Zhao, Xiaochun,Jiang, Lvqi,Yi, Wenbin
supporting information, p. 4012 - 4016 (2018/09/20)
A sulfonic anhydride-promoted direct trifluoromethylthiolation using NaSO2CF3 has been developed. The simple and practical strategy enabled the direct introduction of SCF3 moiety into unexplored arene scaffolds under reductant- and metal-free condition at room temperature. (Figure presented.).
17β-HSD1 AND STS INHIBITORS
-
Page/Page column 84, (2010/11/25)
The present invention relates to novel substituted steroid derivatives which represent selectiv inhibitors of the 17β-hydroxysteroid dehydrogenase type I (17β-HSD1) and, in addition, which may represent inhibitors of the steroid sulphatase, as well as to their salts, to pharmaceutical preparations containing these compounds and to processes for the preparation of these compounds. Furthermore, the invention concerns the therapeutic use of said novel substituted steroid derivatives, particularly their use in the treatment or prevention of steroid hormone dependent diseases or disorders, such as steroid hormone dependent diseases or disorders requiring the inhibition of 17β-hydroxysteroid dehydrogenase type I and/or steroid sulphatase enzymes and/or requiring the lowering of the endogenous 17β-estradiol concentration.
