14745-89-2

Basic information

• Product Name: 1,3-bis(4-chlorobenzyl)-N-(2-chloroethyl)-1,3,2-diazaphosphinan-2-amine 2-oxide
• CAS NO: 14745-89-2
• Molecular Formula: C₁₉H₂₃Cl₃N₃OP
• Molecular Weight: 446.7382
• Mol File: 14745-89-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 561.9°C at 760 mmHg
• Flash Point: 293.6°C
• Density: 1.37g/cm³
• Vapor Pressure: 1.18E-12mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: 1,3-bis(4-chlorobenzyl)-N-(2-chloroethyl)-1,3,2-diazaphosphinan-2-amine 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis(4-chlorobenzyl)-N-(2-chloroethyl)-1,3,2-diazaphosphinan-2-amine 2-oxide(14745-89-2)
• EPA Substance Registry System: 1,3-bis(4-chlorobenzyl)-N-(2-chloroethyl)-1,3,2-diazaphosphinan-2-amine 2-oxide(14745-89-2)

Safety Data

• Hazardous Substances Data: 14745-89-2(Hazardous Substances Data)

Usage

Chemical structure

1,3-bis(4-chlorobenzyl)-N-(2-chloroethyl)-1,3,2-diazaphosphinan-2-amine 2-oxide is a phosphoramide mustard with a diazaphosphorinane oxide moiety and two 4-chlorobenzyl groups.

Potential use

It has potential use in medicinal and pharmaceutical applications.

Anticancer activity

It has been studied for its potential anticancer activity, particularly in the treatment of leukemia and lymphoma.

Mechanism of action

It works by inhibiting DNA replication and causing cell death in cancer cells.

Ongoing research

Research is ongoing to further understand and develop the potential therapeutic uses of this chemical in the treatment of various forms of cancer.

Upstream product

• 6533-30-8 2-chloro-1,3-bis-(4-chloro-benzyl)-[1,3,2]diazaphosphinane 2-oxide 
• 689-98-5 chloroethylamine