147511-70-4

Basic information

• Product Name: (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]- 3,5-dihydrosy-6-heptane acid,
• Synonyms: (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]- 3,5-dihydrosy-6-heptane acid,;(3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid (+)-phenylethylamine salt;(3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydrosy-6-heptaneacid,(+)phenylethylamine;6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl] -3,5-dihy -droxy-, (3R,5S,6E)-, coMpd. with (R)-MethylbenzeneMethanaMine (1:1);y-6-heptenoic acid tert-butyl ester (3R,5S)-7-[2 cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-
• CAS NO: 147511-70-4
• Molecular Formula: C₈H₁₁N*C₂₅H₂₄FNO₄
• Molecular Weight: 542.648
• EINECS: 1312995-182-4
• Mol File: 147511-70-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 14.2 °C at 760 mmHg
• Appearance: /
• Density: 0.691 g/cm³
• CAS DataBase Reference: (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]- 3,5-dihydrosy-6-heptane acid,(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]- 3,5-dihydrosy-6-heptane acid,(147511-70-4)
• EPA Substance Registry System: (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]- 3,5-dihydrosy-6-heptane acid,(147511-70-4)

Safety Data

• Hazardous Substances Data: 147511-70-4(Hazardous Substances Data)

Usage

Uses

Pitavastatin (+)-Phenylethylamine Salt is a salt analog of Pitavastatin (CAT# P215580), which is a HMG-?CoA reductase inhibitor useful in lowering cholesterol levels. Pitavastatin (+)-Phenylethylamine Salt can be used in the preparation of novel crystals of pitavastatin calcium for treatment of hypercholesterolemia, familial hypercholesterolemia, and atherosclerosis.

Upstream product

• 154057-58-6 <2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl>methyltriphenylphosphonium bromide 
• 154057-56-4 3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)-quinoline 
• 121660-11-5 2-cyclopropyl-4-(4-fluorophenyl)-3-(hydroxymethyl)quinoline 
• 121660-37-5 2-cyclopropyl-4-(4-fluorophenyl)-3-formylquinoline 
• 586966-54-3 (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoic acid tert-butyl ester 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 

Downstream Products

• 147526-32-7 pitavastatin calcium salt 

Relevant articles and documents

NOVEL POLYMORPHS OF PITAVASTATIN CALCIUM

The present invention provides a solid of pitavastatin tert-butyl ester and process for its preparation. The present invention also provides a novel crystalline form of pitavastatin calcium, process for its preparation and pharmaceutical compositions comprising it.