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14759-09-2

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14759-09-2 Usage

General Description

1-(2-Piperidin-4-yl-ethyl)-piperidine is a compound belonging to the class of organic compounds known as dialkylpiperazines. Dialkylpiperazines are compounds containing a piperazine moiety that carries two alkyl groups. Known to be soluble in many organic solvents due to its organic nature, this compound also belongs to the sub-class of piperazine rings, a group of organic compounds sharing a common cyclical structure made up of six members with two nitrogen atoms at opposite vertices. The safety, toxicity, and exact utilization of 1-(2-Piperidin-4-yl-ethyl)-piperidine are not widely reported in scientific literature, indicating that it may not be widely used or produced on a commercial scale. However, derivatives of piperidine are commonly found in many pharmaceuticals and active pharmaceutical ingredients, suggesting possible uses in medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 14759-09-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,7,5 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 14759-09:
(7*1)+(6*4)+(5*7)+(4*5)+(3*9)+(2*0)+(1*9)=122
122 % 10 = 2
So 14759-09-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H24N2/c1-2-9-14(10-3-1)11-6-12-4-7-13-8-5-12/h12-13H,1-11H2

14759-09-2Relevant articles and documents

Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptor

Nencini, Arianna,Castaldo, Cristiana,Comery, Thomas A.,Dunlop, John,Genesio, Eva,Ghiron, Chiara,Haydar, Simon,Maccari, Laura,Micco, Iolanda,Turlizzi, Elisa,Zanaletti, Riccardo,Zhang, Jean

, p. 401 - 418 (2014/04/17)

α7 nicotinic acetylcholine receptor agonists are promising therapeutic candidates for the treatment of cognitive impairment. As a follow up of our internal medicinal chemistry program we investigated a novel series of α7 nAChR agonists. Starting from molecular docking studies on two series of molecules recently developed in our laboratories, an alternative scaffold was designed attempting to combine the optimal features of these previously identified urea and pyrazole compounds. Based on our previous SAR knowledge and on predicted drug-like properties, a small library was synthesized in parallel manner, affording compounds with excellent α7 nAChR activity, selectivity and preliminary ADME profile.

SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS

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Page/Page column 99; 124, (2009/12/05)

This invention relates to a new sordarin derivative or a pharmaceutically acceptable salt thereof, which has antimicrobial activities (especially, antifungal activities), to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases in a human being or an animal.

Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain

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Page/Page column 19, (2008/06/13)

The present invention concerns novel benzenesulphonamide compounds, defined by formula I and the description, their method of preparation and their use in therapy.

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