1476038-44-4

Basic information

• Product Name: C₂₄H₂₀F₃NO₅
• CAS NO: 1476038-44-4
• Molecular Weight: 459.422
• Mol File: 1476038-44-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₀F₃NO₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₀F₃NO₅(1476038-44-4)
• EPA Substance Registry System: C₂₄H₂₀F₃NO₅(1476038-44-4)

Safety Data

• Hazardous Substances Data: 1476038-44-4(Hazardous Substances Data)

Upstream product

• 10349-38-9 p-methoxyphenylisonitrile 
• 70783-32-3 2,2,2-trifluoro-1-(4-phenoxyphenyl)-ethanone 
• 64-19-7 acetic acid 
• 5470-34-8 4-methoxyformanilide 

Relevant articles and documents

Novel ultrasound-promoted parallel synthesis of trifluoroatrolactamide library via a one-pot passerini/hydrolysis reaction sequence and their fungicidal activities

An ultrasound-promoted one-pot Passerini/hydrolysis reaction sequence has been developed for the synthesis of trifluoroatrolactamide derivatives using a diverse range of trifluoroacetophenones and isonitriles in acetic acid. Parallel synthesis in a centrifuge tube using a noncontact ultrasonic cell crusher was used in this study as an efficient method for the rapid generation of combinatorial trifluoroatrolactamide libraries, and subsequent biochemical evaluation of the resulting compounds indicated that they possessed excellent broad-spectrum fungicidal activities. N-(4-chlorophenyl)-2-(4-ethylphenyl)-3,3, 3-trifluoro-2-hydroxypropanamide and N-(4-chlorophenyl)-3,3,3-trifluoro-2- hydroxy-2-(4-methoxyphenyl)propanamide, in particular, showed significant fungicidal activities against all of the fungal species tested in the current study.