147643-57-0 Usage
Description
(S)-2-(3,4-Dichlorophenyl)pent-4-enoic acid, with the chemical formula C11H10Cl2O2, is a carboxylic acid featuring an unsaturated side chain. This molecule is characterized by a central pentene chain, to which a 3,4-dichlorophenyl group is attached at one end, and a carboxylic acid group is present at the other end. Its unique structure and potential pharmacological properties make it a valuable compound in the fields of organic synthesis and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
(S)-2-(3,4-Dichlorophenyl)pent-4-enoic acid is used as a starting material for the production of various pharmaceuticals. Its unique structure allows it to serve as a building block in the development of new drugs, contributing to the advancement of medical treatments.
Used in Agrochemicals:
In addition to its applications in the pharmaceutical industry, (S)-2-(3,4-Dichlorophenyl)pent-4-enoic acid is also utilized as a starting material for the synthesis of agrochemicals. This contributes to the development of new products aimed at enhancing agricultural productivity and crop protection.
Used in Organic Synthesis:
(S)-2-(3,4-Dichlorophenyl)pent-4-enoic acid is employed as a key intermediate in organic synthesis, where it can be used to create a variety of functional materials and complex molecular structures. Its versatility in this field is attributed to its reactive carboxylic acid group and the presence of the unsaturated pentene chain.
Check Digit Verification of cas no
The CAS Registry Mumber 147643-57-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,6,4 and 3 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 147643-57:
(8*1)+(7*4)+(6*7)+(5*6)+(4*4)+(3*3)+(2*5)+(1*7)=150
150 % 10 = 0
So 147643-57-0 is a valid CAS Registry Number.
147643-57-0Relevant articles and documents
Design, synthesis, and optimization of balanced dual NK1/NK 3 receptor antagonists
Hanessian, Stephen,Jennequin, Thomas,Boyer, Nicolas,Babonneau, Vincent,Soma, Udaykumar,Mannoury La Cour, Clotilde,Millan, Mark J.,De Nanteuil, Guillaume
supporting information, p. 550 - 555 (2014/06/09)
In connection with a program directed at potent and balanced dual NK 1/NK3 receptor ligands, a focused exploration of an original class of peptidomimetic derivatives was performed. The rational design and molecular hybridization of a novel phenylalanine core series was achieved to maximize the in vitro affinity and antagonism at both human NK1 and NK3 receptors. This study led to the identification of a new potent dual NK1/NK3 antagonist with pKi values of 8.6 and 8.1, respectively.
Carboxy substituted acylic carboxamide derivatives
-
, (2008/06/13)
The present invention relates to novel carboxy substituted acyclic carboxamide derivatives of formula (1)): STR1and stereoisomers and pharmaceutically acceptable salts thereof and their use as tachykinin receptor antagonists. Such antagonists are useful in the treatment of tachykinin-mediated diseases and conditions disclosed herein including: asthma, cough, and bronchitis.
Piperidine derivatives useful as neurokinin antagonists
-
, (2008/06/13)
Compounds of formula I STR1 wherein Q1, Q2, Q3, and Q4 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of neurokinin A and useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.
