147646-73-9Relevant articles and documents
A Mild and Selective C-3 Reductive Alkylation of Indoles
Appleton, Julie E.,Dack, Kevin N.,Green, Andrew D.,Steele, John
, p. 1529 - 1532 (1993)
In the presence of triethylsilane and trifluoroacetic acid, the reaction between indoles and aldehydes in dichloromethane at 0 deg C, results in good yields of C-3 reductively alkylated products.The transformation is most effective for the preparation of 3-(arylmethyl)indoles 6 from aromatic aldehydes.
