147663-61-4

Basic information

• Product Name: 2-Propen-1-ol, 3-(3,5-dimethoxyphenyl)-
• CAS NO: 147663-61-4
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Mol File: 147663-61-4.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-ol, 3-(3,5-dimethoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-ol, 3-(3,5-dimethoxyphenyl)-(147663-61-4)
• EPA Substance Registry System: 2-Propen-1-ol, 3-(3,5-dimethoxyphenyl)-(147663-61-4)

Safety Data

• Hazardous Substances Data: 147663-61-4(Hazardous Substances Data)

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 29584-64-3 ethyl 3,5-dimethoxycinnamate 
• 76104-60-4 methyl 3-(3,5-dimethoxyphenyl)acrylate 
• 20767-04-8 (E)-3,5-dimethoxycinnamic acid 
• 29577-41-1 3-(3,5-dimethoxyphenyl)-2-propyn-1-ol 
• 1499120-79-4 (E)-1-(3-chloroprop-1-en-1-yl)-3,5-dimethoxybenzene 

Downstream Products

• 1380294-17-6 (E)-N-(1-(3,5-dimethoxyphenyl)hexa-1,5-dien-3-yl)acrylamide 
• 1380294-25-6 (E)-6-(3,5-dimethoxystyryl)-5,6-dihydropyridin-2(1H)-one 
• 1380293-92-4 (E)-1-(3,5-dimethoxyphenyl)hexa-1,5-dien-3-ol 
• 1380294-00-7 (E)-1-(3,5-dimethoxyphenyl)hexa-1,5-dien-3-yl acrylate 
• 1380294-08-5 (E)-6-(3,5-dimethoxystyryl)-5,6-dihydro-2H-pyran-2-one 
• 1326634-95-0 trans,trans,trans-1-(3,5-dihydroxyphenyl)-6-(4-hydroxyphenyl)-1,3,5-hexatriene 
• 125187-46-4 3,5-dimethoxycinnamaldehyde 

Relevant articles and documents

Synthesis of chiral fluorine-containing compounds via Pd-catalyzed asymmetrical allylations of dimethyl 2-fluoromalonate using sulfonamide-pyridine ligands

Chiral o-aniline sulfoxides serving as chiral sulfurous source were synthesized, from which new sulfonamide-pyridine ligands were made in three-steps. These compounds proved to be efficient S,N-ligands for enantiocontrol of palladium-catalyzed allylic sub

Enantioselective α-functionalization of 1,3-dithianes by iridium-catalyzed allylic substitution

An iridium-catalyzed asymmetric allylic substitution reaction with 2-alkoxy carbonyl-1,3-dithianes has been achieved with high regio- and enantioselectivities. The transformation provides a new method for the enantioselective α-functionalization of dithianes. The corresponding dithiane-containing products are easily converted into many other derivatives with high yields and enantioselectivities.

Biocatalytic dynamic kinetic reductive resolution with ketoreductase from: Klebsiella pneumoniae: The asymmetric synthesis of functionalized tetrahydropyrans

Ketoreductase from growing cells of Klebsiella pneumoniae (NBRC 3319) acts as an efficient reagent for converting racemic α-benzyl/cinnamyl substituted-β-ketoesters to the corresponding β-hydroxy esters with excellent yields and stereoselectivities (ee and de >99 %). The reactions described herein followed a biocatalytic dynamic kinetic reductive resolution (DKRR) pathway, which is reported for the first time with such substrates. It was found that the enzyme system can accept substituted mono-aryl rings with different electronic natures. In addition, it also accepts a substituted naphthyl ring and heteroaryl ring in the α-position of the parent β-ketoester. The synthesized enantiopure β-hydroxy esters were then synthetically manipulated to valuable tetrahydropyran building blocks.