1476807-78-9

Basic information

• Product Name: 2-(1,4,5,6-tetrahydropyrimidin-2-yl)benzonitrile
• Synonyms: 2-(1,4,5,6-tetrahydropyrimidin-2-yl)benzonitrile
• CAS NO: 1476807-78-9
• Molecular Weight: 185.228
• Mol File: 1476807-78-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(1,4,5,6-tetrahydropyrimidin-2-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1,4,5,6-tetrahydropyrimidin-2-yl)benzonitrile(1476807-78-9)
• EPA Substance Registry System: 2-(1,4,5,6-tetrahydropyrimidin-2-yl)benzonitrile(1476807-78-9)

Safety Data

• Hazardous Substances Data: 1476807-78-9(Hazardous Substances Data)

Upstream product

• 109-76-2 Trimethylenediamine 
• 91-15-6 phthalonitrile 

Relevant articles and documents

Microwave-assisted cascade cycloaddition for C-N bond formation: An approach to the construction of 1,4,5,6-tetrahydropyrimidine and 2-imidazoline derivatives

An efficient strategy for the synthesis of various 1,4,5,6- tetrahydropyrimidine and 2-imidazoline derivatives has been reported. The reactions proceeded from nitriles with ethylenediamine or 1,3-diaminopropane via cascade cycloaddition in the presence of CuL2 (L = 2-hydroxy-2-phenylacetate) to afford the corresponding 1,4,5,6- tetrahydropyrimidine or 2-imidazoline derivatives under reflux conditions or microwave irradiation in excellent yields.