147700-73-0

Basic information

• Product Name: 1,3-Dioxolane, 4,5-bis(chlorodiphenylmethyl)-2,2-dimethyl-, (4R,5R)-
• CAS NO: 147700-73-0
• Molecular Formula: C31H28Cl2O2
• Molecular Weight: 503.468
• Mol File: 147700-73-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxolane, 4,5-bis(chlorodiphenylmethyl)-2,2-dimethyl-, (4R,5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxolane, 4,5-bis(chlorodiphenylmethyl)-2,2-dimethyl-, (4R,5R)-(147700-73-0)
• EPA Substance Registry System: 1,3-Dioxolane, 4,5-bis(chlorodiphenylmethyl)-2,2-dimethyl-, (4R,5R)-(147700-73-0)

Safety Data

• Hazardous Substances Data: 147700-73-0(Hazardous Substances Data)

Upstream product

• 37031-29-1 (-)-dimethy-2,3-O-isopropylidene-L-tartrate 
• 93379-48-7 (R,R)-TADDOL 

Downstream Products

• 147898-97-3 2,3-O-isopropylidene-1,4-di-O-methyl-1,1,4,4-tetraphenyl-L-threitol 
• 193892-67-0 (4R,5R)-5-[(methoxy)(diphenyl)methyl]-2,2-dimethyl-α,α-diphenyl-1,3-dioxolane-4-methanol 
• 147700-75-2 (4S,5S)-2,2-dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanamine 
• 1399830-39-7 (3aR,6S,7aR)-tetrahydro-2,2-dimethyl-4,4,6,7,7-pentaphenyl-4H-1,3-dioxolo[4,5-d][1,2]oxaphosphorin 6-oxide 
• 1399830-08-0 (3aR,7aR)-tetrahydro-6-methoxy-2,2-dimethyl-4,4,7,7-tetraphenyl-4H-1,3-dioxolo[4,5-d][1,2]oxaphosphorin 6-oxide 
• 1399829-65-2 (4S,5S)-2,2-dimethyl-N4,N5,α,α,α',α'-hexaphenyl-1,3-dioxolane-4,5-dimethanamine 
• 1399829-68-5 (3aS,8aS)-hexahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-6H-1,3-dioxolo[4,5-e][1,3]diazepin-6-one 
• 1399830-18-2 (3aS,8aS)-hexahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-6H-1,3-dioxolo[4,5-e][1,3]diazepine-6-thione 
• 1399829-70-9 (3aS,8aS)-hexahydro-2,2,5,7-tetramethyl-4,4,8,8-tetraphenyl-6H-1,3-dioxolo[4,5-e][1,3]diazepin-6-one 
• 1399829-72-1 (3aS,8aS)-3a,5,8,8a-tetrahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-6-[(phenylmethyl)sulfanyl]-4H-1,3-dioxolo[4,5-e][1,3]diazepine 
• 1399829-74-3 (3aS,8aS)-3a,5,8,8a-tetrahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-6-{[(1R)-1-phenylethyl]sulfanyl}-4H-1,3-dioxolo[4,5-e][1,3]diazepine 
• 1399830-17-1 (3aS,8aS)-3a,5,8,8a-tetrahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-6-{[(1S)-1-phenylethyl]sulfanyl}-4H-1,3-dioxolo[4,5-e][1,3]diazepine 
• 1399829-92-5 (3aS,8aS)-hexahydro-6-methoxy-2,2-dimethyl-4,4,5,7,8,8-hexaphenyl-4H-1,3-dioxolo[4,5-e][1,3,2]diazaphosphepine 
• 1399829-94-7 (4S,5S)-N4-[4-(diphenylphosphino)phenyl]-2,2-dimethyl-N5,α,α,α',α'-pentaphenyl-1,3-dioxolane-4,5-dimethanamine 

Relevant articles and documents

Chiral enantiopure bis(thio)ureas derived from TADDOL and their carboxylate complexation capacity

New chiral enantiopure ureas and thioureas with (R,R)-TADDOL backbone were synthesized. Bis-(thio)ureas with C2 symmetry were obtained from TADDOL iso(thio)cyanates and bifunctional amino-(thio)ureas from TADDAMINE, respectively. These were tested for car

Investigations concerning the syntheses of TADDOL-derived secondary amines and their use to access novel chiral organocatalysts

A structurally carefully diversified library of novel TADDOL-derived chiral secondary amines was synthesized and investigated for their applicability to obtain new organocatalysts like chiral Lewis bases and chiral phase-transfer catalysts. The scope and limitations of the developed syntheses routes to access these catalysts as well their catalytic performance in different benchmark reactions were systematically investigated. The most powerful of the catalysts prepared was found to be highly useful for the phase-transfer catalyzed α-alkylation of glycine Schiff base (high yields and up to 93% ee). Georg Thieme Verlag KG Stuttgart · New York.

Synthesis of mono- and diunsaturated esters of TADDOL

The synthesis of fourteen new mono- and diesters of (4R,5R)-2,2-dimethyl- α,α,α′,α′-tetraphenyl-1,3-dioxolane-4, 5-dimethanol (TADDOL) is reported. This study shows that esterifications of TADDOL (1) with acid chlorides, derived from normal and α,β- unsat