147879-18-3Relevant articles and documents
Asymmetric Synthesis via Heterocyclic Intermediates, L Trichloroacetimidates, II Asymmetric Synthesis of α-Amino Acid Benzyl Esters via the Bisbenzyl Bislactam Ether of cyclo(-L-Val-Gly-)
Groth, Ulrich,Schmeck, Carsten,Schoellkopf, Ulrich
, p. 321 - 324 (2007/10/02)
The diketopiperazine cyclo(-L-Val-Gly-) (1) can be O-alkylated under mild acidic reaction conditions with the alkyl trichloroacetimidates 2 to the corresponding bisalkyl bislactim ethers.Alkylation of the bisbenzyl bislactim ether anion of cyclo(-L-Val-Gl