14795-21-2Relevant articles and documents
Protecting-group-free synthesis of glycosyl 1-phosphates
Edgar, Landon John G.,Dasgupta, Somnath,Nitz, Mark
supporting information; experimental part, p. 4226 - 4229 (2012/09/22)
Glycosyl 1-phosphates enriched in the α-anomer are obtained without the use of protecting groups in two steps starting from the free hemiacetal. Condensation of free hemiacetals with toluenesulfonylhydrazide yields a range of glycosylsulfonohydrazide donors which can be oxidized using cupric chloride in the presence of phosphoric acid and the coordinating additive 2-methyl-2-oxazoline to give useful yields of the fully deprotected glycosyl 1-phosphates.