148183-79-3Relevant articles and documents
A general method for the preparation of 5-trifluoromethylated oxazoles from α-amino acids
Kawase, Masami,Miyamae, Hiroshi,Kurihara, Teruo
, p. 749 - 756 (2007/10/03)
The reactions of N-acyl-N-benzyl-α-amino acids (1) or N-acylprolines (5) with trifluoroacetic anhydride in the presence of pyridine afford 5- trifluoromethyloxazoles (2 or 7) in good yields. The reaction could proceed through the transient formation of me