1482-50-4 Usage
Description
11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE, also known as 5β-Dihydrocortisol, is a steroid hormone derivative of Cortisol (H714615). It belongs to the class of glucocorticoids, which are primarily produced by the zona fasciculata of the adrenal gland. 11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE plays a crucial role in various physiological processes due to its structural and functional properties.
Uses
Used in Pharmaceutical Industry:
11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE is used as a therapeutic agent for various medical conditions due to its anti-inflammatory, immunosuppressive, and anti-allergic properties. It helps in managing symptoms of chronic inflammation, autoimmune diseases, and allergies by modulating the immune system and reducing inflammation.
Used in Endocrinology:
In the field of endocrinology, 11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE is utilized for the treatment of adrenal gland disorders and other hormone-related conditions. Its glucocorticoid nature allows it to regulate the body's response to stress and maintain proper metabolic balance.
Used in Research and Development:
11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE serves as an essential compound in the research and development of new drugs and therapies targeting inflammation, immune system modulation, and hormone-related disorders. Its unique properties make it a valuable tool for understanding the mechanisms of action and potential applications in various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1482-50-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,8 and 2 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1482-50:
(6*1)+(5*4)+(4*8)+(3*2)+(2*5)+(1*0)=74
74 % 10 = 4
So 1482-50-4 is a valid CAS Registry Number.
InChI:InChI=1/C21H32O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12,14-16,18,22,24,26H,3-11H2,1-2H3/t12?,14-,15-,16-,18+,19-,20-,21-/m0/s1
1482-50-4Relevant articles and documents
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Shirasaka,Tsuruta
, p. 277 (1959)
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NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF
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Page/Page column 87, (2015/02/02)
Described herein are neuroactive steroids of the Formula (I): (Formula (I)) or a pharmaceutically acceptable salt thereof; wherein R1a and R1b are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.
METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID
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Paragraph 0315; 0316, (2013/06/05)
Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxy-steroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.
