148217-40-7

Basic information

• Product Name: Atorvastatin Lactam Sodium Salt Impurity
• Synonyms: Atorvastatin Lactam Sodium Salt Impurity;(βR,δR)-5-(4-Fluorophenyl)-2,3-dihydro-β,δ-dihydroxy-3-(1-Methylethyl)-2-oxo-4-phenyl-3-[(phenylaMino)carbonyl]-1H-pyrrole-1-heptanoic Acid SodiuM Salt;Atorvastatin Pyrrolidone Analog (USP);Atorvastatin Pyrrolidone Analog;Atorvastatin Lactam Calcium Salt;sodium (3R,5R)-7-(5-(4-fluorophenyl)-3-isopropyl-2-oxo-4-phenyl-3-(phenylcarbamoyl)-2,3-dihydro-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
• CAS NO: 148217-40-7
• Molecular Formula: C33H34FN2NaO6
• Molecular Weight: 596.6210332
• Product Categories: Aromatics;Chiral Reagents;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 148217-40-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 133-136°C
• Appearance: /
• Storage Temp.: Amber Vial, -20°C Freezer, Under Inert Atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• Stability: Light Sensitive
• CAS DataBase Reference: Atorvastatin Lactam Sodium Salt Impurity(CAS DataBase Reference)
• NIST Chemistry Reference: Atorvastatin Lactam Sodium Salt Impurity(148217-40-7)
• EPA Substance Registry System: Atorvastatin Lactam Sodium Salt Impurity(148217-40-7)

Safety Data

• Hazardous Substances Data: 148217-40-7(Hazardous Substances Data)

Usage

Description

Atorvastatin Lactam Sodium Salt Impurity is a cyclic impurity derived from Atorvastatin, a widely used cholesterol-lowering drug. It is characterized by its white to off-white solid appearance and is formed as a result of photodegradation.

Uses

Used in Pharmaceutical Industry:
Atorvastatin Lactam Sodium Salt Impurity is used as a research compound for understanding the degradation pathways and stability of Atorvastatin. This knowledge is crucial for ensuring the drug's efficacy, safety, and quality during its shelf life.
Additionally, it may be utilized as a reference material in the development of analytical methods for detecting and quantifying impurities in Atorvastatin, which is essential for maintaining the drug's quality and complying with regulatory standards.
Used in Quality Control:
Atorvastatin Lactam Sodium Salt Impurity is used as a reference standard in quality control processes to verify the accuracy and reliability of analytical methods employed in the pharmaceutical industry. This helps in the detection and quantification of impurities, ensuring the drug meets the required purity standards.
Used in Drug Development:
In the field of drug development, Atorvastatin Lactam Sodium Salt Impurity can be used as a starting material or intermediate in the synthesis of new compounds with potential therapeutic applications. Understanding the properties and reactivity of this impurity can contribute to the design and development of novel drugs with improved pharmacological profiles.