1483-07-4

Basic information

• Product Name: Albizziin
• Synonyms: L-(-)-2-AMINO-3-UREIDOPROPIONIC ACID;L-2-AMINO-3-UREIDOPROPIONIC ACID;L-ALBIZZIIN;L-ALBIZZIINE;L-ALBIZZINE;H-ALA(UREIDO)-OH;H-BETA-(UREIDO)-ALANINE;H-BETA-(UREIDO)-ALA-OH
• CAS NO: 1483-07-4
• Molecular Formula: C₄H₉N₃O₃
• Molecular Weight: 147.13
• EINECS: 216-046-1
• Product Categories: Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Inhibitors;Herpes Viruses
• Mol File: 1483-07-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 217°C (dec.)
• Boiling Point: 267.22°C (rough estimate)
• Flash Point: 170.987 °C
• Appearance: White powder
• Density: 1.4397 (rough estimate)
• Vapor Pressure: 3.95E-06mmHg at 25°C
• Refractive Index: 1.5700 (estimate)
• Storage Temp.: 2-8°C
• Solubility: Methanol (Slightly), Water (Slightly)
• PKA: 2.15±0.10(Predicted)
• Merck: 13,210
• CAS DataBase Reference: Albizziin(CAS DataBase Reference)
• NIST Chemistry Reference: Albizziin(1483-07-4)
• EPA Substance Registry System: Albizziin(1483-07-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 1483-07-4(Hazardous Substances Data)

Usage

Description

Albizziin is a white powder with a variety of applications in different industries due to its unique properties as a glutamase inhibitor, a glutaminyl-tRNA synthetase inhibitor, and an intermediate in the synthesis of heterocycles. It also has potential as an effector group in affinity chromatography.

Uses

Used in Pharmaceutical Industry:
Albizziin is used as a glutamase inhibitor for its role in regulating the activity of glutamase enzymes, which are involved in various biological processes and can be targeted for therapeutic purposes.
Used in Biochemical Research:
Albizziin is used as a glutaminyl-tRNA synthetase inhibitor, which can help in studying the function and regulation of this enzyme in protein synthesis and other cellular processes.
Used in Chemical Synthesis:
Albizziin is used as an intermediate in the synthesis of heterocycles, which are important structural components in many pharmaceuticals and natural products.
Used in Chromatography:
Albizziin is used as a potential effector group in affinity chromatography, a technique used to separate and purify specific target molecules based on their interactions with the effector group.

InChI:InChI=1/C4H9N3O3/c5-2(3(8)9)1-7-4(6)10/h2H,1,5H2,(H,8,9)(H3,6,7,10)/t2-/m1/s1

Upstream product

• 590-28-3 potassium cyanate 
• 515-94-6 (S)-2,3-diaminopropionic acid 
• 56073-44-0 β-(3-hydroxyureido)-L-alanine 
• 91338-47-5 β-Ureido-L-α-tosylamino-propionsaeure 
• 1482-97-9 (S)-2,3-diaminopropanoic acid hydrochloride 
• 52809-07-1 quisqualic acid 

Downstream Products

• 91643-98-0 (S)-2-benzoylamino-3-ureido-propionic acid methyl ester 
• 96846-03-6 (S)-2-[4-(Benzyloxycarbonyl-methyl-amino)-benzoylamino]-3-ureido-propionic acid 

Relevant articles and documents

Synthesis of L-Quisqualic Acid: A General Method for Enantio-efficient Synthesis of β-Aminoalanine Derivatives

A general method for the enantio-efficient synthesis of β-aminoalanine derivatives, which involves intramolecular transfer of the amino substituent from the α-carboxy to the β-carbon atom wia an azetidinone is described with its application to an efficient synthesis of the neuroexcitatory quisqualic acid in an optically pure state.

L-β-(5-Hydroxy 2 pyridyl) alanine and L-β-(3 hydroxyureido) alanine from streptomyces

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