1483-25-6

Basic information

• Product Name: 1H-Tetrazole, 5-phenoxy-1-phenyl-
• CAS NO: 1483-25-6
• Molecular Formula: C13H10N4O
• Molecular Weight: 238.249
• Mol File: 1483-25-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1H-Tetrazole, 5-phenoxy-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Tetrazole, 5-phenoxy-1-phenyl-(1483-25-6)
• EPA Substance Registry System: 1H-Tetrazole, 5-phenoxy-1-phenyl-(1483-25-6)

Safety Data

• Hazardous Substances Data: 1483-25-6(Hazardous Substances Data)

Usage

Structure

Tetrazole derivative with a phenoxy and phenyl group attached to the 5th and 1st positions, respectively

Potential applications

Medicinal chemistry, drug development, synthesis of biologically active compounds

Usage

Building block in organic synthesis, reagent in chemical reactions

Researched activities

Antimicrobial, antifungal, and antitumor

Value

Versatile and valuable compound in scientific and industrial applications

Upstream product

• 1455-92-1 5-methylsulfanyl-1-phenyl-1H-tetrazole 
• 1154397-00-8 1-phenyl-5-(vinylsulfonyl)-1H-tetrazole 
• 139-02-6 sodium phenoxide 
• 917905-41-0 1-phenyl-5-(phenylsulfanyl)-1H-tetrazole 
• 800393-28-6 1-phenyl-5-(phenylsulfonyl)-1H-tetrazole 
• 108-95-2 phenol 
• 86-93-1 1-phenyl-1H-tetrazole-5-thiol 
• 3206-44-8 5-methanesulfonyl-1-phenyl-1H-tetrazole 
• 14210-25-4 5-Chloro-1-phenyltetrazole 

Downstream Products

• 113720-82-4 PdCl₂(5-phenoxy-1-phenyltetrazole)*1,2-dichloroethane 
• 54246-57-0 5-methoxy-1-phenyl-1H-tetrazole 
• 5097-82-5 5-hydroxy-1-phenyltetrazole 
• 135-98-8 sec-Butylbenzene 
• 103-65-1 phenylpropane 
• 98-82-8 Isopropylbenzene 
• 71-43-2 benzene 
• 5097-82-5 5-phenyl-1H-tetrazolone 
• 5378-52-9 phenyl-1H-tetrazole 
• 108-95-2 phenol 
• 100-41-4 ethylbenzene 
• 825-55-8 2-phenylthiophene 

Relevant articles and documents

Expanding the Potential of Heteroaryl Vinyl Sulfones

The easily available vinyl sulfone 3 showed great potential for new applications in several fields such as organic synthesis and bioconjugate formation. This was demonstrated by performing a systematic assessment of its reactivity in Michael, radical, and cycloaddition reactions. Heteroaryl vinyl sulfone 3 presented excellent output in terms of reactivity and selectivity, proving superior to phenyl vinyl sulfone 1 and with clear advantages over bis-sulfone 2. This behavior might be due to the conformational and orbital control exerted by the tetrazole unit according to DFT calculations. Moreover, some alternative transformations to the Julia-Kocienski olefination on the obtained products are also described.

Tetrazoles: LVII. Preparation and chemical properties of 1-substituted 5-arylsulfonyltetrazoles

Oxidation of 1-substituted 5-arylsulfanyltetrazoles with m-chloroperoxybenzoic acid and NaIO4 in the presence of RuCl 3 leads to the formation of the 5-arylsulfonyltetrazoles. The microwave activation significantly accelerates the ox

Tetrazoles. 33. New method for obtaining functionally substituted tetrazoles

The interaction of 5-methylsulfonyl-1-phenyltetrazole with C-, N-, and O-nucleophiles at 18-20°C gives high yields of 1-phenyltetrazoles that are functionally substituted on the carbon atom of the heteroring. Prospects are examined for the use of 5-methyl