148324-13-4Relevant articles and documents
Chemoenzymatic carbon-carbon bond formation leading to non-carbohydrate derivative. Stereoselective synthesis of pentamycin C-11-C-16 fragment
Shimagaki,Muneshima,Kubota,Oishi
, p. 282 - 286 (2007/10/02)
Chemoenzymatic formation of 8 from an aldehyde 5 and dihydroxyacetone phosphate 6 was achieved by the use of fructose 1,6-diphosphate aldolase as a catalyst. Transformation of 8 to 20, corresponding to pentamycin C-11-C-16 fragment, was accomplished via 18a and 18b by chemical processes.