148431-35-0Relevant articles and documents
Application of Hexafluoroacetone as Protecting and Activating Reagent in Amino Acid and Peptide Chemistry. N-Substituted Glycine Derivatives from Iminodiacetic Acid
Burger, Klaus,Neuhauser, Horst,Worku, Anteneh
, p. 107 - 120 (2007/10/02)
3-Carboxymethyl-2,2-bis(trifluoromethyl)-oxazolidin-5-one 2, obtained on reaction of iminodiacetic acid 1 and hexafluoroacetone, represents a preparative useful intermediate for the synthesis of unsymmetrically substituted derivatives of the dicarboxylic acid 1.The N-substituted glycine derivatives obtained are interesting candidates for peptide modification.Keywords: Iminodiacetic Acid, Hexafluoroacetone, 3-Carboxymethyl-2,2-bis(trifluoromethyl)oxazolidin-5-one, N-Substituted Glycine Derivatives